Zomig

 3 tablets of the drug Zomig.
 Zomig - protivomigrenoznoy with drug activity.

The pharmacological action of Zomig

By action and effectiveness is an absolute analog of Zomig Zolmitriptan. Both drugs have moderate activity towards 5HT1A receptors. Under the influence of the drug afferent fibers of the trigeminal nerve innervate the dura mater of the brain blood vessels and blood vessels. In animal experiments, scientists have noted that Zomig causes vasoconstriction associated with the suppression of previously released and calcitonin gene-related peptide, substance P and vasoactive intestinal peptide. That is what provokes the improvement at any migraine attacks. Frequently Zomig, ratings patients confirmed this reduces the intensity of the pain (which occurs after an hour), reduces the likelihood of nausea and vomiting, and photophobia and phonophobia, are associated with migraine.

In addition to these properties, Zomig has a good effect on the brain, the core alignment mechanism involved in the formation and development of migraine attacks. This, in fact, explains the very robust effect, especially with repeated use of the drug.

In any migraine attacks observed vasodilation, which is due to the activation of reflex excitation, which is supported on the orthodromic trigeminal nerve fibers and parasympathetic innervation in the blood vessels of the brain. Zomig and blocks the release of reflex arousal vasoactive intestinal peptide, and thereby takes the pharmacological action of the drug.

Product form

Film-coated tablets, yellow, biconvex, round, are marked "Z" on one side. The blisters are packed in 3 of the tablet.

Indications for use Zomig

Zomig is indicated for the relief of migraine attacks.

Contraindications

According to the instructions for Zomig, it is contraindicated in:

  • coronary heart disease;
  • uncontrolled hypertension;
  • the cerebral circulation;
  • transistor ischemic attacks in history;
  • vasospastic angina;
  • WPW syndrome or arrhythmias;
  • used together with ergotamine or other drugs that are derivatives thereof;
  • hypersensitivity to any component of the formulation.

With great care the drug is prescribed to elderly patients.

Instructions Zomig: how to use

 Packing drug Zomig.
 According to the instructions for Zomig, the recommended dose of migraine attacks - 2, 5 mg (1 tablet).

If symptoms persist or re-occur for 24 hours, then re-appointment is possible Zomig. But it is worth noting that it is not necessary to take a second dose immediately after the first must go through at least 2 hours. If the second dose did not produce the desired effect, then in subsequent cases, need to take 5 mg. Clinically significant effect can be achieved within one hour after a single dose.

It is recommended to take the medication as soon as possible after the onset of migraine pain, but reviews of Zomig argue that the effectiveness of the drug does not depend on this. It is stated that the total daily dose in any case should not exceed 10 mg, even with repeated bouts of pain.

Patients with moderate or mild impairment of liver function, as well as patients with all sorts of impaired renal function dose adjustment is required.

It is noted that while the reception of 50 mg Zomig or analogs overdose occurs, which is a symptom of sedation.

side effects

Admission Zomig, reviews confirm this, can be accompanied by a number of side effects, manifested in violation of sensitivity, dizziness, feeling of tightness and heaviness in the limbs, headaches, dry mouth, nausea, abdominal pain, ischemic colitis, hemorrhagic diarrhea, muscle weakness, myalgia , palpitations, tachycardia, polyuria, frequent urination.

Also, there may be a variety of allergic reactions after taking Zomig, patient testimonials confirm the appearance of angioedema, anaphylactic reactions and urticaria.

But in general, the drug is transferred easily enough, and all the adverse effects are expressed either moderately or very easy to have the character of a transistor and tested without further treatment.

Conditions and terms

Store Zomig should be at a temperature no higher than 30 about With the reach of children less than 2 years.





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