Zocor - a drug that limits the production of cholesterol.
Zocor is applied in conditions characterized by elevated cholesterol because it is peculiar to influence its level reduce the concentration of thyroglobulin, lipoprotenov low density.
The active ingredient of the drug - simvastatin, takes effect two weeks after initiation of therapy, the maximum possible effect observed after 4-6 weeks.
There are reviews of Zocor, indicating that after the end of the drug cholesterol becomes the same as before the treatment.
Release tablets Zocor.
Analogs Zokora - Vero simvastatin Simvakard, Simvalimit, Simvor, Simvakol - drugs with the same active ingredient.
Zocor is prescribed by the instructions in the primary hypercholesterolemia and a second type b, in patients with a high risk of developing atherosclerosis in those cases when diet therapy was ineffective at hyperlipoproteinemia, hypertriglyceridemia, combined hypercholesterolemia.
Good reviews of Zocor, is used to prevent a heart attack, TIAs brain stroke.
Zokora Guide: how to use
The drug is taken once / day, in the evening.
The starting dose for moderate and mild hypercholesterolemia is 5 mg, with severe hypercholesterolemia - 10 mg / day. If the therapy proves ineffective, the dose no earlier than a month increase, given that the maximum permissible dose - 80mg.
When ischemia Zocor is prescribed in an initial dose of 20 mg, which is gradually increased to 40 mg every month.
For patients suffering from chronic renal failure, those receiving nicotinamide, fibrates, or cyclosporin, the recommended initial dose of 5 mg, and the maximum allowable - 10 mg / day.
In spite of the same active substance analogues Zokora can be produced in other dosages or dosage forms, so the doctor has to make the appointment.
Treatment with Zocor can cause vomiting, diarrhea, nausea, gastralgia, bloating, constipation, jaundice, acute pancreatitis, hepatitis, dizziness, insomnia, fatigue, peripheral neuropathy, paresthesia, cramps, blurred vision, taste disturbance, angioedema, eosinophilia, vasculitis, fever, alopecia, arthralgia, redness of the skin, arthritis, thrombocytopenia, urticaria, palpitation, acute renal failure, anemia, deterioration of potency.
Instructions for Zocor is contraindicated in liver disease in the acute stage, increased liver enzymes, liver failure, hypersensitivity. Do not take Zocor nursing, pregnant women, children up to 18L.
Zocor may increase the effects of anticoagulants, which can cause bleeding. It should also be borne in mind that it increases the concentration of the active substance in the blood of digoxin.
It increases the likelihood of rhabdomyolysis combination drug with fibrates, niacin in large doses, cytostatics, erythromycin, immunosuppressants, itraconazole, ketoconazole, clarithromycin.
The bioavailability of simvastatin reduced Colestipol and Cholestyramine, so it can be taken only after 4h after these preparations.