Xylometazoline

 Xylometazoline drops
 Xylometazoline belongs to the vasoconstrictor (decongestant) topical application. In other words, it is a brilliant representative of the most notorious "nose drops" around which is broken so many copies regarding their damage with prolonged use. But it must be acknowledged that in certain situations, when nasal breathing is too difficult to use vasoconstrictor within the symptomatic treatment is fully justified.

Product form

Xylometazoline made several Russian pharmaceutical enterprises in the form of sprays and nose drops, the concentration of active ingredient is 0, 05% or 0, 1%. Packaging is a plastic (rarely - a glass) bottle with sprayer (to spray) or without (drip), placed in a cardboard box.

In the role of the active ingredient xylometazoline hydrochloride acts, ie in this case the trade name of the drug actually coincides with the international.

Analogs ksilometazolina

Analogues ksilometazolina the domestic pharmaceutical market quite a lot. This is due to the popularity among the population vasoconstrictor that can quickly relieve distressing symptoms sometimes so cold. But in addition to the full ksilometazolina analogues (drugs with the same active substance, but differ on trade name), there are many other decongestants, other than in the chemical structure but are similar in pharmacological action.

Given the above, it seems appropriate in the framework of this article to list only the total ksilometazolina counterparts, to which include the following drugs:

  • Snoop spray (Germany);
  • Ksilin drops (Russia);
  • Suprema-NHS, Spray (India);
  • Xymelin IVF with menthol (Sweden);
  • Otrivin, spray for children (Switzerland);
  • Asterisk ERA, drops and sprays (Vietnam);
  • Tizin xylitol spray (France);
  • Rinonorm spray (Germany);
  • For the nose spray (India).

It should be added that in some analogues ksilometazolina (or in the preparation of this) as excipients contains natural ingredients (menthol, eucalyptus). Therefore, we can recommend to scrutinize the instructions in the ksilometazolina before buying, which will specify the full composition of the drug.

Pharmacological action

Its vasoconstrictor effect xylometazoline implements through the stimulation of alpha-adrenergic receptors located in the nasal mucosa. Such adrenomimeticheskoe action leads to increased smooth muscle tone (in this case - the peripheral wall of the smooth muscle of blood vessels). As a consequence - docked inflammation, relieve swelling and nasal breathing is restored.

Positive feedback on ksilometazolina patients are largely due to the speed of his actions, which develops within a few minutes, and the effect lasts (depending on the severity of the common cold) up to 10 hours.

Indications

The instructions to xylometazoline can read the following indications for its use:

  • catarrhal infections, burdened by rhinitis (inflammation of the nasal mucosa) and sinusitis (inflammation of the nasal sinuses);
  • allergic (non-infectious) rhinitis and sinusitis;
  • hay fever (seasonal pollen allergy);
  • evstahiit (when inflammation goes to the auditory organs - the middle ear cavity and the Eustachian tube);
  • as an adjuvant symptomatic treatment within the complex treatment of otitis media.

Regulations on the use of xylometazoline

Instruction Xylometazoline differentiates concentration and amount of drug received, depending on the age of the patient. For children up to 6 years it is recommended to use xylometazoline in a concentration of 0, 05% of 1-2 drops 1-2 times a day (drops) or 1 injection 1-2 times per day (spray). Children 6 to 12 years - 2-3 drops 3-4 times per day 0, 05% solution or 1 drop 3-4 times per day 0, a 1% solution (drops) or 1 injection of 2-3 times day 0, 1% solution (spray). Finally, children over 12 years and adults appoint 2-3 drops 2-3 times per day 0, 1% solution (drops), and in the form of a spray - as well as children over 6 years.

It is important not to exceed the established instructions ksilometazolina treatment: no more than 7-10 days (and for children, and even less - 3-5 days).

Contraindications

Apart from the general to almost all drugs contra - are hypersensitive - Xylometazoline has a number of other restrictions on admission:

  • high blood pressure, heart palpitations, or atherosclerotic vascular changes;
  • glaucoma (in its closed-form);
  • endocrine disorders (diabetes, hyperthyroidism);
  • nonproductive (dry) and chronic rhinitis.

In diabetes and cardiovascular disease receiving ksilometazolina still possible, but with caution.

Xylometazoline during pregnancy

We should also mention the use of xylometazoline in pregnancy. Especially that the issue of interest to many women. So: Xylometazoline during pregnancy is not recommended. Such limitations drug "shall" its vasoconstrictor properties. It is not that the way of the use of xylometazoline pregnancy specialists lit "red light". However, in recommending the drug, the doctor must be sure that the benefits for the woman outweighs the potential risk to the child. Similarly, the use of xylometazoline in pregnancy is limited by its reception and lactation.  Snoop - similar Xylometazoline

side effect

Judging by the reviews of xylometazoline, the drug is generally well tolerated. However, this does not exclude certain negative phenomena, including the abuse of the drug.

For reviews of ksilometazolina show "drying" he nasal mucosa. This is manifested in the presence of irritation, burning, stinging. There may be a reverse effect opposite therapeutic (so-called "rebound effect") when it begins to flow from the nose, a feeling of congestion, mucous swells. There could be some generalized symptoms such as nausea, dizziness, tachycardia, arrhythmias, blurred vision, which is also mentioned in a review of xylometazoline.

Cautions

Long-term use or overdose ksilometazolina fraught with the risk of atrophic changes in the mucosa of the nasopharynx and the transition of infection or allergic rhinitis in the form of medication.

Attention needs the drug by children and persons of retirement age.

Chronic rhinitis restricts the use of xylometazoline because of the high probability of atrophy of the nasal mucosa.

Instructions for storage ksilometazolina

Shelf life ksilometazolina is 2 to 3 years (depending on the manufacturing plant). The bottle with the drug should be stored at room temperature.





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