Alpha-tocopherol acetate (vitamin E)

 Alpha-tocopherol acetate - oral solution
 Alpha-tocopherol acetate - natural antioxidant, vitamin E, belongs to a group of fat-soluble vitamins.

Release form and composition

Vitamin E is produced in the form of:

  • Capsules of 100 mg;
  • Clear oil oral solution with a content of 1 ml of active substance in an amount of 50 mg, 100 mg and 300 mg.

The active ingredient of both forms is just alpha-tocopherol acetate, auxiliary - soybean oil. Composition capsule shell comprises gelatin (52, 75 mg), glycerol (16, 80 mg) and the methylhydroxybenzoate (0, 4 mg).

Indications

Alpha-tocopheryl acetate according to the instructions prescribed for:

  • Muscular dystrophy (decrease in muscle strength and volume);
  • Amyotrophic lateral sclerosis (a disease of the CNS, resulting in the deterioration of the motor activity of the limbs and facial muscles);
  • Cardiomyopathy (disease of the heart muscle);
  • Peripheral vascular spasm;
  • Liver disease;
  • Potency disorders (sexual activity), and violation of spermatogenesis (the process of formation of gametes);
  • Some kinds of skin diseases including psoriasis;
  • Failure of the menstrual cycle;
  • Risk of miscarriage.

In pediatrics tocopherol acetate is indicated for:

  • Malnutrition (eating disorder causing underweight);
  • Scleroderma (systemic disease of the skin);
  • Hypervitaminosis D (excessive vitamin D in the body).

As the antioxidant drug used in the treatment of eye, cardiovascular diseases, to reduce the side effects in the treatment with chemotherapeutic drugs. There is evidence that it enhances the effectiveness of anticonvulsant therapy for epilepsy (in the case of elevated blood level of lipid peroxidation products).

Contraindications

Use of alpha-tocopherol acetate is contraindicated in hypersensitivity to the components included in the medicament.

Dosage and Administration

The preparation in any dosage form is usually administered 100-300 mg per day, the maximum - 1 g

The dosage and duration of treatment of hypovitaminosis E determined by the physician individually depending on the severity of the condition.

side effects

When using the Alpha-tocopherol acetate may develop allergic reactions. In high doses it can cause diarrhea, and epigastric pain. With prolonged use at a dose of 400 IU per day may develop:

  • Blurred vision;
  • Disorders of sexual function;
  • Fatigue;
  • Dizziness;
  • Asthenia;
  • Gastralgia;
  • headache;
  • Thrombophlebitis;
  • Nausea;
  • Diarrhea;
  • Thromboembolism.

Cautions

Vitamin E capsules and the solution should be used with caution in myocardial infarction, severe cardiosclerosis and high risk of thromboembolism.

Analogs

Analogues of alpha-tocopherol acetate are:

  • As active substances - alpha-tocopherol-UBF, Vitamin E, Vitamin E Doppelgerts, B-complex;
  • According to the mechanism of action - calcium pantothenate, nicotinamide, Metilmetioninsulfoniya chloride (vitamin U), pyridoxal phosphate Pyridoxine-Vial, pyridoxine, riboflavin, Flavinat.

Terms and conditions of storage

The drug is sold without a prescription. Store in a dry place out of direct sunlight, at a temperature of 15-25 ° C. Shelf life - 2 years.





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