Vazokardin - a drug that belongs to a group of funds, lowering blood pressure.
The active ingredient of the drug - metoprololatartrat.
The active ingredient helps to reduce blood pressure Vazokardina and reduce the heart's demand for oxygen. It has a fairly high efficiency in long-term treatment of angina and high blood pressure, which is confirmed and reviews Vazokardine patients.
The maximum amount of active substance in plasma is achieved at 1, 5-2 hours after application. The first application of bioavailability is 50% on subsequent receptions - 70%. Excreted by the kidneys, the half-life - 3, 5 hours.
According to the instructions, Vazokardin used for such diseases:
- arterial hypertension;
- Supraventricular tachycardia.
Vazokardin well enough help as a preventive agent for migraine, as evidenced by reviews of Vazokardine patients treated him as such.
Instructions for use and dose Vazokardina
According to the instructions, Vazokardin taken orally. It is recommended to take Vazokardin at one and the same time of day is best in the morning, in order to achieve greater efficiency.
Tablets Vazokardina swallow without chewing, and washed down with a little water. When receiving Vazokardina necessary to monitor the heart rate and blood pressure.
The duration of treatment and the dose the doctor sets, reviews Vazokardine professionals warn against self-medication with this drug.
Hypertension: Vazokardina dose is 50 mg two times a day. If necessary, you can assign up to 200 mg per day. The drug may be administered once or twice per day.
Angina: according to instructions Vazokardin in this disease may be administered at a dose of 50 mg twice a day. If necessary, the dose can be increased.
Myocardial infarction after acute phase: Vazokardina dose is 100 mg two times a day.
Irregular heartbeat: the daily dose is 100 mg, it is divided into two stages. In case of insufficient effectiveness of the dose can be increased or additionally assign antiarrhythmic therapy.
Migraine Prophylaxis: receiving Vazokardin 50-100 mg twice a day.
The maximum permissible dose is 200 mg. In diseases of the liver may require an adjustment of the recommended dose.
Do not abruptly cancel the drug. You must gradually reduce the dose Vazokardina to complete discontinuation.
In general, the drug is well tolerated, what can be read in a review of Vazokardine.
In rare cases, there are side effects:
- From the gastrointestinal tract: stomach pain, vomiting, nausea, impaired stool, dry mouth, impaired fat metabolism, hepatitis, increased liver enzyme levels in the blood;
- CNS and PNS: convulsions, paresthesia, fatigue, headache, loss of memory and attention, vertigo, insomnia, nervousness, anxiety, hallucinations, tinnitus;
- Allergic reactions: bronchospasm, rhinitis, and allergic conjunctivitis, pruritus, rash, photophobia, sweating, urticaria, psoriasis, alopecia, angioedema (very rare).
It is also possible weight gain, change in taste, joint pain, decreased libido, latent diabetes, reduced potency, asthma, blurred vision, Peyronie's disease.
According to the instructions, Vazokardin has the contraindications:
- Lactase deficiency;
- Syndrome malabsorbtsiiglyukozo-galactose;
- Sinoatrial block;
- Atrioventricular block II and III;
- Sick sinus syndrome;
- Decompensated heart failure;
- State of shock;
- Suspected myocardial infarction;
- Peripheral circulatory disorders;
- bronchial asthma;
- Metabolic acidosis;
- Lung disease with chronic obstruction;
- Pregnancy and lactation;
- Patients under 18 years old.
Precautions should be prescribed the drug during surgery, vaccination, psoriasis, depression.
Do not drive a car and operate dangerous machinery while taking Vazokardina.
In overdose Vazokardina possible nausea, vomiting, decreased blood pressure, impaired consciousness, bronchospasm, cardiogenic shock, cyanosis, heart failure up to coma and cardiac arrest.
Vazokardina antidote does not exist. With an overdose of prescribed gastric lavage, chelators, symptomatic therapy. In severe cases, intensive care therapy.