Valz - peripheral vasodilator used in the treatment of diseases of the cardiovascular system.
Pharmacological action Valza
According to the instructions Valz is a peripheral vasodilator that is specific AT1 blocker, hypotensive action and does not inhibit the angiotensin converting enzyme.
According to the instructions Valz produced in the form of oval, biconvex, film-coated tablets yellow labeled «V» on the one hand, lateral risk and on the other hand, 40 mg and 160 mg, and pink tablets marked «V» on the one hand , side risk and risk on the other side of 80 mg Valium planimetric packages. One tablet contains Valza:
By analogues Valza mechanism of action and of belonging to a group of pharmacological drugs include:
Valz drug is prescribed for hypertension and congestive heart failure. Valz also part of the complex therapy and is used to improve the survival of patients with acute myocardial infarction complicated by both left ventricular systolic dysfunction and left ventricular failure.
In accordance with the instructions Valz taken orally, with some liquid irrespective of food intake. Dosage depends on the disease, namely:
When hypertension initial dose of 80 mg to a possible increase to 160 mg once a day for 4 weeks;
In chronic heart failure, the dose is 40 mg twice a day, gradually increasing to 80 mg;
Under stable hemodynamics after myocardial infarction, the dose is 20 mg twice a day, gradually increasing to 40 mg, 80 mg and 160 mg twice daily;
For mild to moderate hepatic dysfunction without cholestasis the dose of 80 mg per day.
In accordance with the instructions Valz is contraindicated in pregnancy and lactation, children under the age of 18 years, in hepatic dysfunction associated with bile duct obstruction, lactose intolerance, malabsorption syndrome, galactose and glucose, galactosemia, kidney failure, and increased sensitivity to components drug.
Precautions Valz prescribed for hypotension, hypertrophic obstructive cardiomyopathy, hyponatremia, hyperkalemia, bilateral renal artery stenosis or artery only kidneys, mitral and aortic stenosis, primary hyperaldosteronism and in conditions associated with a reduction in circulating blood volume.
Application Review Valza causes complications from the various systems of the body, namely:
Neutropenia and thrombocytopenia (hematopoietic system);
Back pain, arthritis, muscle cramps, myalgia, and arthralgia (musculoskeletal system);
Renal dysfunction and acute renal failure (urinary system);
Reduction in hemoglobin and hematocrit, increased concentrations of serum urea nitrogen, hypercreatininemia, elevated liver transaminases and hyperbilirubinemia (laboratory values).
Also, the use of Valza reviews could lead to:
Skin rash and itching;
Upper respiratory infection;
In cases of overdose application Valza Review causes a decrease in blood pressure.
In accordance with the instructions Valz must be stored out of reach of children and protected from light, dry place at room temperature up to 30 ° C. Shelf life of the drug in compliance with the recommendations is 3 years.