Urosulfan belongs to the sulfa drugs.
The active ingredient - sulfakarbamid. The preparation has antibacterial action against Gram-negative and Gram-positive bacteria. Especially high activity has Urosulfan against E. coli and staphylococcus. This medication has a bacteriostatic effect by blocking the absorption of microorganisms parabens, disrupting the processes of synthesis of folic acid required for the formation of purine and pyrimidine compounds. As a result, it stops the growth and development of the bacterial cell, and instead of PABA microorganism cell captures sulphanylamide preparation.
Urosulfan rapidly absorbed from the gastrointestinal tract, blood plasma creates a sufficiently high concentration of the drug. The drug is excreted mainly excreted by the kidneys. High concentration Urosulfana urinary has antibacterial effect on microorganisms causing urinary tract infections. Deposition of the drug in the urinary tract occurs.
The instructions to Urosulfanu indicated that the drug is used at purulent infectious diseases of the urinary system:
- cystitis (bladder infection);
- pyelitis (inflammation of the renal pelvis);
- cystopyelitis (combination of inflammation in the renal pelvis and urinary bladder);
- pyelonephritis (inflammation of the renal parenchyma);
- infected hydronephrosis.
According to the instructions, Urosulfan contraindicated in hypersensitive to the components of the drug, blood diseases.
Instructions for use, dosage Urosulfana
The drug is administered orally. Before the appointment Urosulfana to determine sensitivity of microorganisms that caused this pathology, to the drug. The single dosage is from 0 5 to 1d. Multiplicity of reception - three to five times a day. The course of treatment is usually 6-14 days. The maximum daily dosage for children - 2, 5 g for adults - 7d.
Urosulfana dosage at a specific pathology, as well as the duration of treatment with this drug determined by the physician.
The drug Urosulfan fairly well tolerated. Rarely recorded side effects such as headache, nausea, leukopenia, allergic reactions such as skin.
Interaction with other drugs
Do not appoint Urosulfan simultaneously anestezin, novocaine, preparations containing folic acid as a reduction in the therapeutic effect. Joint reception with Urosulfana butadionom, chloramphenicol, butamidom, bukarbanom, anticoagulants, cytostatic, immunosuppressive agents may lead to increased side effects. Urosulfan also enhances the action of hypoglycemic and anticonvulsants.
Application Urosulfana during pregnancy
It should be used with extreme caution given the drug during pregnancy. During lactation, if necessary, use Urosulfana be on time to stop breast feeding.
Urosulfan is available in tablet form. One tablet contains 0, 5g of active compound. The package of 12 tablets.
Analogs of this drug are Euvernil, Uramid, sulfonyl urea.
Before using this drug need to get acquainted with the instructions for Urosulfanu. Use of the drug can only be prescribed by a doctor.