Trimetazidine

 Trimetazidine normalizes the process of consumption and energy production of cells
 Trimetazidine - is a drug belonging to the group of medicines that improve the metabolism (metabolism) in the tissues of neurosensory organs and myocardial conditions in which blood circulation disorders (ischemia).

Mode of action of trimetazidine

Trimetazidine normalizes the process of consumption and energy production (energy metabolism) cells undergo as a result of circulatory disorders oxygen deficiency. In the opinion of Trimetazidine prevents a decrease in intracellular concentration of adenosine triphosphate (ATP), which is the main source of energy necessary for the maintenance of normal cell activity. In addition, the drug helps the proper functioning of membrane ion channels, thus maintaining a constant internal environment (homeostasis) cells.

The instructions to trimetazidina noted that taking it increases resistance to lack of oxygen myocardial cells, the hearing aid and the retina.

The use of trimetazidine in patients with angina pectoris can reduce the incidence of attacks and increases the stability of the myocardium (tolerance) to physical stress. Also, during therapy the drug significantly reduced the use of nitroglycerin patients.

In the opinion of Trimetazidine improves hearing and reduces, and in some cases completely eliminates vertigo in Meniere's disease.

If ingestion Trimetazidine almost completely and very rapidly absorbed through the mucous membranes of the gastrointestinal tract. Its bioavailability is 90%. Maximum concentration in the blood two hours after taking the initial dose. Trimetazidine is derived mainly kidneys unchanged.

Indications trimetazidina

This drug is used for long-term treatment of coronary heart disease in combination therapy, and as monotherapy.

According to the instructions Trimetazidine can also be used for the treatment of hearing loss, tinnitus, vestibular disorders cochle-caused ischemic. In addition, indications are trimetazidina chorioretinal vascular disorders.

Dosage trimetazidina

 Trimetazidine is taken orally two - three times a day for 20, 0 mg
 The drug is taken orally two - three times a day for 20, 0 mg. Duration of trimetazidine determined by your doctor individually for each patient, depending on the particular clinical picture of the disease.

Cautions

Trimetazidine does not affect the performance of work requiring a good psychomotor reactions, in particular the ability of management of vehicles.

Contraindications

According to the instructions Trimetazidine is contraindicated during pregnancy and breastfeeding, as well as all persons with hypersensitivity to the components of the drug.

Side effects of trimetazidine

In the opinion of Trimetazidine is well tolerated by patients. Very rarely, it can lead to allergic reactions that manifest the appearance of pruritus and rash. Very rarely during treatment with trimetazidine nausea, vomiting, epigastric pain. If you have individual intolerance to this drug, then you trimetazidina analogues are also contraindicated.

Analogs trimetazidina

Analogues of any drug referred to means having the same with him the international nonproprietary name. Accordingly, analogues of trimetazidine are Adeksor, Kardazin, Kardimaks, Kardital, Trikard, etc. Energoton.

Storage conditions trimetazidina

In accordance with the instructions Trimetazidine should be stored in a dark, dry place at room temperature. The shelf life is two years.





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