Tempalgin - combined analgesic and antipyretic drug.
Pharmacological action tempalgin
The structure includes a non-narcotic analgesic tempalgin metamizole sodium and anxiolytic tempidon. Metamizole function blocks cyclooxygenase 1 and 2, which are involved in the formation of prostaglandins - inflammatory compounds pyrogenic oriented. Also Metamizole able to stabilize cell membranes and inhibits the synthesis of its own pyrogens. These properties allow the drug has a strong antipyretic, analgesic and mild anti-inflammatory effect.
Tempidon has anxiolytic effects, stimulating the central n-cholinergic receptors. It eliminates the fear, tension, positive effect on the emotional component of pain. Tempidon composed tempalgin extend analgesic action Metamizole and potentiates it, increasing by 2 - 3 times. Both components of this drug are well absorbed from the digestive tract, it is converted in the liver to metabolites and excreted primarily in the urine.
Tempalgin drug release tablets, coated tablets. 1 tablet contains 500 mg of metamizol sodium and 20 mg tempidona.
Tempalgin instructions for use in the event of fever in infectious and inflammatory diseases, pain reliever as an accessory after the diagnostic procedures or surgeries. There are indications for tempalgin slack in cases of visceral pain in combination with antispasmodics, for example, hepatic, renal colic, and others. The patients give positive feedback about tempalgin with moderate or mild pain - toothache, headache, muscle, joint, painful menstruation, including in patients with increased nervousness.
Tempalgin of instructions can not be used when it is intolerance, in some diseases of the blood from germs oppression blood (leukopenia, agranulocytosis, aplastic anemia), liver (acute hepatic porphyria, hepatic failure, some hereditary fermentopathy), kidney (renal failure). It is important to take into account contraindications tempalgin such as reduced (less than 100 mm Hg. Art.) Blood pressure, 1 and 3 trimesters of pregnancy, lactation (the drug penetrates well through the placenta and breast milk). Application tempalgin in children under 14 years of age is not recommended.
Instructions for use tempalgin
If there are indications for tempalgin, it is taken orally after a meal, drinking plenty of fluids. The recommended dose for adults - 1 tablet 3 - 4 times a day (maximum permissible use tempalgin a dosage of 6 tablets per day). Children from the age of 14 can take one pill 2 times per day. If you plan to dental intervention, 30 minutes before the procedure, you can take 1 tablet of this tool. Like any analgesic and antipyretic, without medical supervision of the patient medication can not be used for more than 3 - 5 days. At ARI, if the patient's medical history is not burdened by convulsions, indication for tempalgin will be the body temperature of 38 ° C and 5 above.
Composition tempalgin incompatible with alcohol. Nor should when receiving this drug simultaneously use colloidal blood substitutes, penicillin, opacifying agents, cytostatic drugs.
The drug is not recommended for course admission, it is necessary to abolish as soon as soon as possible. In the case of the reception longer than 7 days required monitoring blood tests and liver function.
Contraindications to tempalgin also a sharp pain in the stomach to detect its cause (in the background you can skip the anesthesia clinic of acute abdomen).
The drug can reduce the concentration of attention and speed of reaction, during the reception it is not recommended to engage in hazardous work possible.
Side effects tempalgin
Tempalgin according to the instructions has a number of undesirable effects. It inhibits the formation of blood and can cause agranulocytosis, leukopenia or thrombocytopenia. During possible reception of xerostomia, jaundice, increased bilirubin and hepatic enzymes in blood, changes in blood pressure, dizziness, kidney function disorders, allergic reactions up to anaphylactic shock.