Silhouette - an oral contraceptive product, which has anti-androgenic effect.
Pharmacological action silhouette
Included in the tablet silhouette components stimulate the inhibition of ovulation, endometrial changes in the structure and motility of the fallopian tubes, as well as the increase in the viscosity of cervical mucus.
According to the instructions, the silhouette is produced in the form of round film-coated, biconvex white or nearly white tablets engraved with «G53» on one side of 2 mg in blister packs of PVC. One tablet contains 30 mcg of ethinyl estradiol and 2 mg of dienogest, 47, 66 mg of lactose monohydrate, 1, 3 mg potassium polyacrylate, 10, 46 mg of corn starch, 0, 65 mg hypromellose 2910 and 1, 3 mg of magnesium stearate.
The composition of the film coating of tablets include the silhouette 3 mg of white Opadry II 85F18422 (1, 2 mg of polyvinyl alcohol, 0, 75 mg of titanium dioxide, 0, 606 mg of macrogol 3350, and 0, 444 mg of talc).
Analogues pills silhouette of the active substance are Janine drugs, Genette and Dietsiklen. By analogues silhouette on the mechanism of action and of belonging to the same pharmacological group includes:
According to the instructions, the silhouette is taken as an oral contraceptive and in the treatment of acne.
According to the instructions, silhouette take every day at the same time, one tablet for three weeks. Subsequent pills silhouette begins a week after the end of the previous package. Typically, for seven days the gap between taking the tablets starts bleeding "cancel." If similar drugs have not been used, the first pills start on the first day of menstruation.
In carrying out an abortion in the first trimester of pregnancy reception immediately appoint silhouette and abortion in the second trimester or postpartum pills begins in 3-4 weeks.
Omitting the reception silhouette for less than 12 hours, protection is not reduced, but if more than 12 hours, the contraceptive protection may be reduced.
According to the instructions, apply the silhouette is contraindicated in case of:
Arterial and venous thromboembolic disease now or in history;
Thrombosis and thromboembolism present or in history;
Jaundice and congenital hyperbilirubinemia;
Smoking at the age of 35 years;
Pancreatitis with severe hypertriglyceridemia now or in history;
State prior to thrombosis;
Vaginal bleeding of unknown origin;
Angiopathy, retinopathy, uncontrolled hypertension and severe dyslipoproteinemia;
Lactase deficiency, lactose intolerance and glucose-galactose malabsorption;
Congenital or acquired predisposition to arterial thrombosis;
Severe forms of liver disease;
Hormone-dependent malignancies genitals or mammary glands;
Migraines with local neurological symptoms;
Pregnancy and lactation;
Hypersensitivity to the drug.
Precautions silhouette prescribed for smoking under the age of 35 years, diabetes, uterine cancer, multiple sclerosis, endometriosis, controlled hypertension, dyslipoproteinemia, phlebitis of superficial veins, congestive heart failure, Crohn's disease, impaired renal function, asthma, liver disease, tetany.
Side effects silhouette
According to reviews, the silhouette can cause stroke, venous and arterial thrombosis, pulmonary embolism and myocardial infarction. The risk of these diseases increases with obesity, coagulation disorder, smoking, thrombophlebitis, varicose veins, presence of hypertension and thrombosis.
Also, according to reviews, is the silhouette of the side effects of the various systems of the body, namely:
Anemia (blood and lymphatic system);
Hypertension, tachycardia, varicose veins, hematoma, hypotension, pain along the vein thrombosis, superficial vein thrombophlebitis, flushing, deep vein thrombosis, pulmonary embolism, myocardial infarction, and cerebrovascular disease (cardiovascular system);
The decrease or increase in body weight, decreased or increased appetite (metabolism and nutrition);
Allergic reactions (immune system);
Bleeding, dyspareunia, pain and tenderness of the breasts, ovarian cysts, vaginitis, vulvovaginitis, breast enlargement, increased vaginal discharge, hyperplasia, endometrium, mastitis, salpingitis, acyclic bleeding or painful bleeding menstrualnopodobnye, leiomyoma, the appearance of the mammary secretion, endometritis , fibrocystic breast dysplasia, cervicitis, bleeding scarce menstrualnopodobnye, lipoma, breast cancer, vulvovaginal pruritus, cancer and endometrium (genitals and breasts);
Depression, sleep disturbances, depressed mood, anorexia, insomnia, aggressiveness, changes in libido and apathy (psyche);
Back pain, arthralgia, myalgia and cramps in the calf muscles (musculoskeletal system).
Also, according to reviews, the silhouette of some women causes liver tumors, venous thromboembolic disorders, vaginitis, hypertension, fungal infection, herpetic lesion of the mouth, feeling of fatigue, arterial thromboembolic disorders, vaginal candidiasis, flu-like symptoms, swelling and chloasma.
In overdose silhouette can cause acute toxicity, vomiting, nausea, and vaginal bleeding.
Storage conditions silhouette
In accordance with the instructions, the silhouette must be stored out of the reach of children and protected from light, dry place at room temperature to 25 ° C. Shelf life in compliance with the recommendations of 2 years.