Suksilep

Suksilep - synthetic anticonvulsant drug used in the treatment of small seizures in adults and children.

Pharmacological action Suksilepa

 Suksilep
 The active ingredient Suksilepa has anticonvulsant effect.

As a result of Suksilepa raises the threshold of epileptic seizures, which is associated with the process of suppression of synaptic transmission in the motor areas of the cerebral cortex.

In addition, trigeminal neuralgia Suksilep according to the instructions has a significant analgesic effect.

Product form

Suksilep drug release in the form of white to orange lid capsules containing 250 mg of active substance - ethosuximide (as a white solidified mass).

Excipients - color yellow, macrogol 400, gelatin, titanium dioxide, and purified water. In bottles of 100 and 120 pieces.

Analogues Suksilepa of the active substance is not released.

Indications Suksilepa

Suksilep according to the instructions indicated for the treatment of small seizures at:

  • Piknolepticheskih absences, including complex or atypical seizures;
  • Juvenile myoclonic seizures;
  • Myoclonic-astatic small seizures.

Contraindications

According to the instructions to take Suksilep contraindicated when:

  • Porphyria;
  • Blood diseases;
  • The liver and kidneys;
  • Pregnancy and lactation;
  • Hypersensitivity to the Suksilepa.

Caution must be exercised in treating patients with Suksilepom mental disorders in history not to trigger the development of side effects such as hallucinations and symptoms of anxiety.

During treatment with Suksilep should not take alcoholic beverages.

Dosing Suksilepa

The daily dosage according to the instructions Suksilepa calculated physician and adjusted individually by the clinical picture of the disease, the body weight, the efficacy of the therapy, and tolerability.

Typically, for adults and children the daily dose Suksilepa early treatment is 5-10 mg / kg body weight. Gradually, no more than twice a week, if necessary, it is increased by 5 mg / kg.

The daily dosage for maintenance treatment Suksilepom reviews for adults is 15 mg / kg for children - no more than 20 mg / kg body weight. The maximum permitted daily dosage should not exceed maintenance dose, increased twice. Failure to comply with the dosing regimen seizures may return.

Suksilep Review effectively taken with food or immediately after it, sharing daily dosage prescribed by your doctor for 2-3 hours. However, in cases where the application Suksilepa causes no side effects, the drug may be taken in one go.

Children under 6 years Suksilep capsules are not prescribed because of the difficulty to comply with the required dosage accuracy. For the treatment of this age group selected formulation containing the active ingredient ethosuximide in liquid dosage form.

The duration of treatment Suksilepom Review is set individually. Typically, therapy is long and it includes the period of 2-3 years since the disappearance of seizures and can then be phasing out Suksilepa with a gradual reduction of dosage.

In the treatment of children over time, increasing the mass of the body does not require increasing doses taken Suksilepa, but the effectiveness of therapy is necessary to check the relevant research.

Prolonged use Suksilepa can lead to generalized seizures.

When receiving Suksilepa at doses significantly higher than therapeutic, may develop the following symptoms:

  • Fatigue;
  • Loss of interest in the surroundings due to lower physical activity;
  • Irritability;
  • The deterioration of sentiment;
  • Irritability.

When using Suksilepa should be aware that simultaneous reception of some medicines may be negative. So, in a joint application Suksilepa:  Capsules Suksilep

  • Carbamazepine - a decrease of the therapeutic effect of the treatment, due to the accelerated clearance from plasma ethosuximide;
  • Since valproic acid and haloperidol - can change the metabolism that lead to an increase or decrease in the concentration of active ingredient in the plasma;
  • With drugs, providing a depressing effect on the central nervous system - can lead to increased side effects.

Side effects Suksilepa

Suksilep on responses can cause side effects, the severity of which depends on the dose received. First of all, they include disorders of the central nervous system are manifested as:

  • Ataxia;
  • Dizziness;
  • headache;
  • Unusual tiredness;
  • Decreased concentration;
  • Depression;
  • Hallucinatory-paranoid disorder;
  • Dyskinesia;
  • Drowsiness;
  • Irritability;
  • Weakness;
  • Aggressiveness;
  • Strengthening tonic-clonic seizures.

Digestive system disorders such as nausea, vomiting, constipation or diarrhea, weight loss and loss of appetite are also dose dependent.

These disorders can usually be avoided by increasing the dose received Suksilepa gradually, as well as combining the drug with food.

Other undesirable behavior when receiving Suksilepa for reviews include:

  • Skin rash, some at least - the development of the syndrome type of systemic lupus erythematosus (of varying severity);
  • Eosinophilia, leukopenia, agranulocytosis and thrombocytopenia, with predisposition - pancytopenia and aplastic anemia;
  • Hiccups, photosensitivity, parkinsonism, albuminuria.

If you notice such symptoms reception Suksilepa Review terminated.

When using Suksilepa can also develop symptoms of myelotoxic action - tonsillitis, fever, and increased bleeding in the event of which it is necessary to inform the treating physician.

storage conditions

Suksilep relates to anticonvulsant drugs, supply of pharmacies are available on doctor's prescription. The recommended shelf life Suksilepa at a temperature not exceeding 25 ° C - 5 years.





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