Nitromintum

 Nitromintum
 Nitromintum - a means to improve the blood supply to the tissues.

Pharmacological action

Nitromintum - is an aerosol form of the drug nitroglycerin, is a tool that extends the peripheral vessels, thus eliminating the symptoms of ischemia.

Nitromintum helps to relax smooth muscle cells, prevents calcium in them. Due to relaxation of muscles dilate blood vessels, reduces preload (venous return) and afterload (resistance to a large range of blood flow), which in turn reduces the oxygen demand of the myocardium.

Also active substance means - nitroglycerin, tend to relax the smooth muscle cells of the gall bladder, esophagus, bronchus, colon (large and small departments) and its sphincters, biliary, urinary ducts.

Nitromintum Spray acts quickly - over one and a half minutes after ingestion and lasts for half an hour.

Product form

Nitromintum release spray.

Indications

Nitromintum according to the instructions indicated for the treatment, prevention of angina relief stenokardicheskie attacks, acute treatment of pulmonary edema.

Instructions for use Nitromintum

Nitromintum use sublingual spray - irrigated area of ​​medicine under the tongue. Keep the can upright with the drug, head up, shake it does not need.

One Press released one dose Nitromintum - 400mkg nitroglycerin.

 Nitromintum Spray
 According to an instruction to stop Nitromintum stenokardicheskie attack is injected in an amount of one or two doses - 400-800mkg. The patient with the introduction of the means to be in a sitting position and hold your breath for half a minute. If necessary, after 15min Nitromintum re-enter - no more than 1, 2 mg (three doses). After each of the administered dose should be closed for 5-10s mouth.

To prevent stenokardicheskie attack injected a single dose of money for 5-10min to load.

When acute left ventricular failure, pulmonary edema injected 1, 6mg Nitromintum. If the therapeutic effect is not due (systole pressure drops below 100 mm), the same dosage administered via 10min.

Older patients dosage change is required.

side effects

Nitromintum spray can cause tachycardia, reduced pressure, headache, cyanosis, collapse, dizziness, nausea, abdominal pain, vomiting, anxiety, disorientation, flushing, burning under the tongue, weakness, lethargy, hypothermia, decreased visual acuity.

In overdose Nitromintum observed reduction in pressure, tachycardia, vomiting, fatigue, diarrhea, headache, drowsiness, fever, redness of the face.

With the introduction of more than 20 mg / kg body weight of the patient appears tachypnea, collapse, cyanosis, disponoe, methemoglobinemia (methemoglobin levels increase in the blood - more than 1%).

For the treatment of an overdose the patient should be transferred in a supine position, lift his legs. If a case is heavy, carried the standard supportive symptomatic treatment aimed at eliminating shock and poisoning. Introducing the adrenaline is impossible.

To resolve methemoglobinemia enter antidotes: 1% methylene blue, ascorbic acid, toluidine blue and conduct dialysis, oxygen therapy, exchange transfusion.

Contraindications Nitromintum

Nitromintum of instruction is contraindicated in case of hypersensitivity to nitroglycerin. With care, he was appointed in hemorrhagic stroke, intracranial hypertension, acute myocardial infarction, chronic heart failure, glaucoma, anemia, arterial hypotension, thyrotoxicosis, severe renal failure, liver failure, pregnancy, breastfeeding.

You can not assign children to Nitromintum 18L.

The hypotensive effect Nitromintum can strengthen its combination with calcium channel blockers, antispasmodics, betaadrenoblokatorami, tricyclic antidepressants.

Also, the hypotensive effect of resources and increases the possibility of the collapse of alcohol.





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