Riabal

 Riabal pills

Riabal - pharmacological agents from the group of m-anticholinergics used for the treatment of diseases of the digestive tract.

Structure and Composition

According to the instructions Riabal issued in the form of a syrup for oral administration, tablets and solution for injection. The active ingredient - prifiniya bromide. 5 ml syrup for oral Riabal 7 contains 5 mg of active substance. Produced the drug in vials of 60 ml, in a cardboard box and manual pipette for dosing.

Tablets Riabal film-coated in 1 tablet of 30 mg prifiniya bromide and auxiliary components (starch, povidone, magnesium stearate, carmellose sodium, colloidal silicon dioxide, talc, titanium dioxide, gelatin, sucrose, carnauba wax). The carton 1 blister with 20 tablets of the drug.

The solution for injection comprises Riabal 7, 5 mg of active substance per 1 ml. The carton 6 ampoules of 2 ml.

Pharmacological action Riabal

According to the instructions Riabal has antiemetic and antispasmodic effect. This drug blocks the m-cholinergic receptors (especially the digestive tract). As a result of decreasing the secretion of hydrochloric acid is reduced peptic activity of gastric juice, inhibits the secretion of pancreas. Riabal also lowers the tone of the smooth muscle fibers of the digestive tract, normalizes peristalsis, promotes gastric emptying.

Once inside Riabal rapidly absorbed, the maximum concentration in the blood is determined after 2 hours. The drug does not cross the blood-brain barrier, it has no toxic effect on the liver, kidney and hematopoietic system, which makes use of Riabal safe for newborns. Withdrawal of the drug in the kidney and intestine. Application Riabal can be lengthy.

Indications

According to the instructions Riabal shown in the following conditions:

  • pain due to functional spasm and increased peristalsis in diseases of the digestive tract (acute / chronic gastritis, peptic ulcer / duodenal ulcer, enterocolitis, irritable bowel syndrome, biliary dyskinesia, acute / chronic cholecystitis, pancreatitis);
  • pain due to spasm of smooth muscles of the urinary tract (urolithiasis, cystitis, algodismenorreya);
  • vomiting (with functional pyloric sphincter spasm in newborns, intracranial hypertension, hyperthermia, after radiation therapy, intolerance of drugs);
  • as a preparation before instrumental and radiological studies of the digestive tract (to reduce gas formation);
  • flatulence, bloating;
  • abdominal cramping psychogenic origin;
  • intestinal baby colic;
  • dyskinesia of the intestine in young children.

Contraindications Riabal

  • hypersensitivity to the drug;
  • glaucoma;
  • gastrointestinal bleeding;
  • prostatic hyperplasia;
  • acute urinary retention;
  • intestinal, megacolon;
  • reflux esophagitis;
  • dynamic ileus;
  • hyperthyroidism;
  • hepatic failure,
  • acute renal failure;
  • Down's syndrome;
  • chronic diseases of the respiratory system;
  • preeclampsia during pregnancy;
  • cerebral palsy in children of central origin;
  • some cardio - vascular system (atrial fibrillation, congestive heart failure, mitral valve stenosis, hypertension).

Use during pregnancy and lactation

According to the instructions Riabal can be used during pregnancy. This drug is not recommended for use if there is a second half of pregnancy toxemia (preeclampsia). Riabal can be assigned during lactation, if the potential benefits outweigh the possible risks to mother and child.

 Riabal drug

Dosing and Administration Riabal

According to the instructions assigned Riabal orally 3 times a day.

Tablets Riabal administered in a daily dose of 90-180 mg (divided into 3 doses). When expressed pain can attack a single dose of 90 mg (3 tablets).

Children from 6 to 12 years Riabal advisable to appoint a daily dose of 60-90mg (divided into 3 doses).

Children under 6 years of drug administered in the form of syrup. Riabal dose for infants is 6 mg per day (divided into 3 doses). For children from 3 to 6 months of medication recommended daily dose of 6-12 mg, from 6 to 12 months - 12 mg per day.

Children 1-2 years old syrup Riabal assigned to 30 mg per day. Children 2-6 years of preparation is recommended at a dose of 30-60 mg per day (divided into 3 doses). Children from 6 to 12 years the daily dose of syrup Riabal is 60-120 mg. In the opinion of Riabal well tolerated in children, and rarely causes side effects.

Injection solution Riabal suitable for subcutaneous, intramuscular or intravenous administration. Single dose for adults is 7, 5-15 mg. The maximum single dose - 30 mg. The daily dose Riabal injections is 22, 5 - 45 mg.

Intravenous administration of the drug should be administered slowly. Riabal be dissolved in a physiological sodium chloride solution. Too rapid introduction Riabal possible sharp drop in blood pressure, leading to shock.

The course of treatment with this drug for 1-2 weeks.

side effect

According to reviews Riabal rarely causes side effects. These include: dry mouth, a breach of accommodation, mydriasis, drowsiness, constipation, tachycardia, increased blood pressure, increased intraocular pressure, nausea, headache. Allergic reactions (angioedema, urticaria, pruritus, rash). In the opinion of Riabal in some cases can cause acute urinary retention.

Overdose Riabalom

Overdosing occurs when the recommended doses are exceeded more than 10 times. Manifests an overdose the following symptoms: weakness, dizziness, tachycardia, orthostatic hypotension, hallucinations. If you exceed the recommended dosage is 100 times paralysis of respiratory muscles.

Treatment is symptomatic. It recommended the introduction of neostigmine (an anticholinesterase effect) and physostigmine.

Interaction with other drugs

Application Riabal enhances the effects of opioid analgesics, neuroleptics, antiparkinsonian drugs, antidepressants.





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