Reksetin

Reksetin - pharmacological agents from the group of antidepressants.

Structure and Composition

According Reksetin instructions issued in the form of tablets, coated tablets, 20 and 30 mg. The active ingredient - paroxetine. Also, the product contains auxiliary components: sodium starch glycolate, calcium hydrogen phosphate dihydrate, magnesium stearate, macrogol, polysorbate, titanium dioxide, hypromellose.

Externally pills Reksetina white, round, biconvex, coated on one side of the risk division.

Produced Reksetin in blister packs of 10 tablets. The carton 2 blisters preparation of 20 or 30 mg.

Pharmacological action Reksetina

According to the instructions Reksetin blocks in the central nervous system uptake of serotonin neurons. Thus the preparation has no effect on the neuronal uptake of dopamine and noradrenaline. Reksetin has anxiolytic and psychoactive effects.

 Reksetin tablets (20 mg)

After oral administration, the drug was well absorbed. The half-life Reksetina average is 24 hours. Withdrawal of the drug by the kidneys (64%) and bowel (36%).

When the liver and kidneys Reksetina concentration in serum increases.

Indications

According to the instructions Reksetin should only be taken under medical supervision, in order to avoid potential complications. The drug is indicated for the following conditions:

  • depression, anxiety disorders of different origin;
  • panic disorders, including agoraphobia;
  • obsessive-compulsive (obsessive compulsive disorder);
  • social phobia;
  • post-traumatic stress disorders;
  • generalized anxiety disorder.

Contraindications Reksetina

  • hypersensitivity to the ingredients of the drug;
  • treatment MAO inhibitors (monoamine oxidase), and 2 weeks after treatment MAO inhibitors;
  • pregnancy, breast-feeding;
  • Children up to age 18 years.

Use during pregnancy and lactation

No clinical data on the safety of Reksitina during pregnancy and lactation. The drug can be used if its potential benefits outweigh the risks connected with its reception.

Dosing and Administration Reksetina

According to the instructions Reksetin taken once a day, in the morning, during a meal. A tablet of the drug can not chew.

In the treatment of depression usually starting dose is 20 mg. In the opinion of Reksetin has the effect gradually. Some patients may need to increase the dose. The maximum daily dose for the treatment of depression Reksetina - 50 mg.

In the treatment of obsessive-compulsive Reksetina initial dose of 20 mg of instructions. If necessary, the dose can be increased to 10 mg every other week. The maximum daily dose Reksetina - 40 mg.

In the treatment of panic disorders it is recommended to take Reksetin 40 mg per day. Therapy should start with 10 mg and increased weekly dose of 10 mg until the desired effect is obtained. The maximum daily dose in this case should not exceed 60 mg. In the opinion of Reksetin early treatment of panic disorder can cause a temporary increase of clinical symptoms.

When social phobia The recommended daily dose is 20 mg. If, after two weeks of treatment, improve the patient's condition is not observed, the dose can be increased Reksetina 10 mg weekly. The maximum daily dose for the treatment of social phobia is 50 mg.

When PTSD Reksetin recommended to take 20 mg per day. The maximum daily dose - 50 mg.

With generalized anxiety disorder Reksetin assigned to 20 mg per day. If necessary, the dose may be increased. The maximum daily dose of the drug is 50 mg.

In elderly patients and in patients with impaired renal function / liver treatment should be started with the dose of 10 mg. The maximum daily dose for these patients should not exceed 20 mg.

side effect

Feedback from the beginning Reksetin application may often cause side reactions that take place in the process of self-therapy.

From the digestive system Reksetin can cause nausea (12% of cases), rarely diarrhea, constipation, loss of appetite. In rare cases, transaminase increase in the serum.

From the nervous system Reksetin, reviews, is 6-9% of cases, drowsiness, tremor, general weakness and fatigue, insomnia, increased sweating. In rare cases, the drug can contribute to the emergence of headaches, irritability, dizziness, somnambulism.

Cardio - vascular system, reviews, Reksetin very rarely causes palpitations, changes in blood pressure, fainting.

 Reksetin tablets (30 mg)

With the genitourinary system, the preparation may cause ejaculation disorder (13%), rarely - changes in libido, difficulty urinating.

From the senses Reksetin in some cases can cause blurred vision, very rarely - an attack of glaucoma.

Allergic reactions, reviews, Reksetin is rare. They can manifest hyperemia of the skin, swelling of the face and extremities, anaphylactic reactions, skin itch.

Interaction Reksetina with other drugs

In combination with MAO inhibitors undesirable interaction occurs.

Not recommended during treatment Reksetinom tryptophan, due to the possibility of side reactions.

During the application of this drug with caution must be taken following drugs: warfarin, sumatriptan, benzodiazepines, tricyclic antidepressants, lithium, digoxin, theophylline.

At simultaneous reception Reksitina with anticonvulsants may increase the frequency of side effects of the latter.

Phenobarbital or combined with Reksetinom lowers its concentration in the blood serum and shortens the period of its half-life.

Diazepam not affect the pharmacokinetics Reksitina and can be used simultaneously.

There was no potentiation of alcohol while taking it with Reksitinom. However, since the drug affects the liver enzyme system, should refrain from drinking alcoholic beverages during treatment.

Cautions

Reksitinom Treatment should be under medical supervision. Women of childbearing age must use contraception while taking this drug.

Analogs Reksetina

Reksetina analogues are the following drugs: adepress, aktaparoksetin, apo paroxetine, Paxil, pliz sirestill, paroxetine. Before replacing analogue Reksitina should consult a doctor.





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