Pyridoxine - vitamin B6, an important link in the metabolism in the body.
The active ingredient of the drug of pyridoxine is pyridoxine hydrochloride (Pharmaceutical name), or rather 2-Methyl-3-hydroxy-4, 5-di- (hydroxymethyl) -pyridine hydrochloride (chemical name).
Available in tablets pyridoxine and pyridoxine in ampoules:
- Tablets for children with an active substance 0, 002 grams in a package of 50 pcs .;
- Tablets for adults, 0, 01 g of pyridoxine hydrochloride in 1 tablet, a package of 50 pcs .;
- 1 ml ampules containing 1%, 2, 5% and 5% solution of pyridoxine hydrochloride, 10 pcs. packaged.
Analogues of the drug are: Vitamin B6, Piridobene, Piradoksin, adermin, Betsilan, Pirivitol, Bedoksin, Benadon, Geksabetalin, Geksabion, Geksavibeks. Pyridoxine hydrochloride is part of many combination medicines, such as: Magne Wb, Perneksin elixir Gepasteril-A-B Gepasteril, lipostabil, Essentiale, and so on.
Pharmacological action Pyridoxine
Pyridoxine stimulate metabolic processes in the body, resulting in a series of chemical transformations transforming into pyridoxal-6-phosphate. This compound is a coenzyme (a substance activating enzymes) necessary for the metabolism of amino acids and lipids. Involved in hemoglobin synthesis, promotes the absorption of glucose by nerve cells, as an essential element for the nervous system in general and the brain in particular.
In the normal state it comes into contact with the liver, meat products, eggs and grains. Lack of pyridoxine can be caused by a nutritional deficiency (low vitamin in foods in the diet of man) or impaired assimilation of vitamin. In this case, there is a need for its external administration in the form of the drug.
Instructions Pyridoxine approves the following indications:
- Insufficient intake of vitamin B6 from food;
- Chorea and other diseases of the central and peripheral nervous system;
- Parkinsonism encephalitis genesis;
- Convulsions in young children;
- Peptic ulcer and duodenal ulcers, and reviews of pyridoxine say that it is effective in treating all kinds of diseases of the intestine, if it is broken suction function;
- Hypochromic and other types of anemia;
- Chronic and systemic diseases of the skin;
- Intoxication anti-TB drugs;
- Exudative diathesis in children;
- radiation sickness;
- Rehabilitation after a serious illness.
Guide to pyridoxine: Dosage and administration
According to the instructions for the prevention of pyridoxine hypo- and beriberi take in the following dosages:
- Children - 0, 002 g / day;
- Adults - 0, 002-0, 005 g / day.
For the treatment use Pyridoxine shown in the following dosage:
- Children - by prescription, depending on body weight;
- Adults - 0, 02-0, 03 g 1-2 times / day
Pyridoxine ampoules administered as subcutaneous, intramuscular and intravenous infusion, dosage:
- Children - 0, 02 g / day;
- Adults - 0, 05-0, 1 g / day.
Application Pyridoxine shown for 2 weeks for children and 1 month for adults (one course). If necessary, repeat the treatment.
Contraindications and side effects
According to the instructions Pyridoxine is contraindicated in case of hypersensitivity to it, which is very rare. Vitamin B6 is needed during pregnancy and lactation, but appointed under these conditions only as directed by a doctor. It should also be careful about the use of pyridoxine in coronary heart disease, gastric ulcer and duodenal ulcers, liver disease.
There are reviews of pyridoxine as substances that cause allergic reactions, such as hives, as well as evidence that it increases the secretion of stomach.
Store protected from light, out of reach of children. Shelf life 3 years.
It can be dispensed without a prescription, but a separate application Pyridoxine is not recommended.