Postinor - postcoital contraceptive for indoor reception.
Structure and Composition
The drug is available in tablets of white color. One tablet contains active substance - 750 ug levonorgestrel. Auxiliary components: lactose monohydrate, potato starch, talc, corn starch, magnesium stearate, colloidal silicon dioxide.
The blisters of 2 tablets.
Postinor - synthetic contraceptive with pronounced antiestrogenic properties and progestin. The use of Postinor inhibits ovulation and fertilization when the sexual contact occurred in the pre-ovulatory phase, at the highest probability of fertilization. Also levonorgestrel causes changes in the endometrium which prevent implantation.
If implantation has already occurred, the application inefficiently Postinor.
After Postinor pregnancy is prevented in 85% of cases. Efficacy is reduced by prolonging the time between sexual intercourse and levonorgestrel (during the first 24 hours - 95% from 24 hours to 48 - 85%, from 48 hours to 72 - 58%). Therefore it is recommended to take the tablets as soon as possible after intercourse.
Recommended dosage of levonorgestrel not affect the metabolism of carbohydrates and fats, as well as blood clotting factors.
According to the instructions Postinor indicated for emergency contraception in case unprotected intercourse.
Contraindications to the instructions of Postinor is:
- severe renal failure;
- hypersensitivity to levonorgestrel;
- Children under sixteen years of age;
- rare hereditary disease (glucose-galactose malabsorption, or lack of lactase lactose intolerance).
The drug is used with caution:
- Crohn's disease;
- in diseases of the biliary tract and liver.
Dosing and dosing regimen Postinor
According to the instructions Postinor taken orally. After unprotected intercourse is recommended to take two tablets within 72 hours. The second tablet is taken not later than 16 hours after the first.
If within three hours after Postinor vomiting occurred, it is necessary to take another pill.
The use of Postinor possible any day of the menstrual cycle. If the menstrual cycle is irregular, before taking Postinor is necessary to exclude the possibility of pregnancy.
After Postinor and before the next menstrual period is recommended to use a local barrier contraceptives (cervical cap, condom). We do not recommend re pills during unprotected sex during the same menstrual cycle, since there is the possibility of increasing the frequency of acyclic bleeding.
In the opinion of Postinor can cause allergic reactions: swelling of the face, skin rash, itching, hives.
Also after Postinor can develop transient side effects that do not require medical treatment:
- delay menstruation for 5-7 days;
- acyclic spotting;
- breast tenderness;
- abdominal pain;
Overdose postinor Review causes increased severity of side effects. In this case, a symptomatic treatment.
Drug interactions with other drugs
The efficacy of levonorgestrel reduce preparations containing St. John's wort, amprekavil, nevirapine, tacrolimus, tretinoin, lansoprazole, oxcarbazepine, topiramate, ritonavir, tetracycline, griseofulvin, rifabutin, ampicillin, ritonavir, and barbiturates, including carbamazepine, phenytoin, primidone.
Levonorgestrel reduces the effectiveness of anticoagulant and hypoglycemic drugs.
Simultaneous administration of drugs inducers of liver metabolism is accelerated Postinor.
According to the instructions Postinor shown only for emergency contraception. We do not recommend re-taking the drug for one menstrual cycle.
In the opinion of Postinor in most cases it does not affect the nature of the menstrual cycle. However, there is a probability of occurrence of delayed menstruation or acyclic bleeding.
Postinor Review may not have the desired effect in violation of the gastrointestinal tract, such as Crohn's disease.
Conditions and terms
Postinor refers to drugs List B with a recommended shelf life of 5 years.