Phenylbutazone is a non-steroidal anti-inflammatory agent of synthetic origin.
This drug has a pronounced analgesic, anti-inflammatory, analgesic and antirheumatic action. The active substance Phenylbutazone is phenylbutazone, which inhibits the activity of cyclooxygenase and reduces the synthesis of prostaglandins. Application of Phenylbutazone can reduce pain, inflammation, restore mobility of the joint. In addition, drug for gout increases the excretion of urate excretion in 2-3 times, reducing their level in the blood. Reduce pain and inflammation Phenylbutazone helps with thrombophlebitis of hemorrhoidal veins and obstetric-gynecological origin, postoperative thrombophlebitis.
Indications for use of phenylbutazone
Phenylbutazone ointment is assigned in the following cases:
articular syndrome in osteoarthritis, acute gout, rheumatoid arthritis, ankylosing spondylitis;
pain in myalgia, arthralgia, phantom pain, neuralgia;
dermatitis, thermal and solar burns, insect bites, skin inflammation by local intramuscular and intravenous injection;
thrombophlebitis, inflammation of hemorrhoids;
soft tissue injury, hematoma, inflammatory infiltrates (accumulation of cellular components in tissue);
stretching the tendons and muscles, tenosynovitis (inflammation of the membranes surrounding the tendon), bursitis (inflammation of periarticular bag).
the pain of burns and injuries, menstrual, dental, and headache;
fever that accompanies colds and infectious diseases.
Instructions for use Phenylbutazone
Phenylbutazone ointment should be applied 2-3 times a day. Superficial lesions do not require rubbing the drug, and with deep processes need to rub ointment Phenylbutazone until complete absorption.
Phenylbutazone tablets administered 200-400 mg (1 tablet - 150 mg) 3-4 times a day. Oral Phenylbutazone should be made during or after a meal. Children older than six months, the recommended single dose of 10 - 100 mg which should be taken 3-4 times a day. Usually 2-5 weeks is sufficient to secure the therapeutic effect of Phenylbutazone tablets.
Application in the form of ointments phenylbutazone can cause allergic skin reactions.
Tablets Phenylbutazone can cause undesirable effects such as:
aphthous stomatitis (with small ulcers), erosive esophagitis (erosion on the esophageal mucosa), glossitis (inflammation of the tongue), gingival, gastrointestinal, hemorrhoidal bleeding, abnormal liver function;