Phenotropil - neuroprotective drugs. The active ingredient - N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. The drug has the ability to direct way to improve the integrative function of the brain. This leads to improved mental abilities, learning, memory consolidation, improving attention. In addition, Phenotropil has anticonvulsant effect anxiolytic properties, improves mood, normalize processes of inhibition and excitation in the brain, has anorexigenic action. In exchange application Phenotropil increases the resistance of brain tissue under hypoxic conditions. Thanks neuroprotective properties Phenotropil indications for its intended purpose and include the pathology caused by the influence of toxic substances, hypoxia. The drug improves blood flow to the brain, stimulates metabolism in neurons.
Phenotropil has the ability to increase the regional blood flow during hypoxia. Improving the energy potential of neurons provides enhanced utilization of glucose. Phenotropil has no effect on the cardiovascular system and respiratory system. It is noted that in the course intake Phenotropil improves visual acuity, increased perception of brightness of colors.
The drug Phenotropil has adaptogenic properties (increases resistance to stressful situations), which is especially evident in the significant emotional and physical stress.
Phenotropil moderately affect motor responses, reduces the inhibitory effect of ethanol on hexenal and brain tissue. It antagonizes cataleptic effect of neuroleptics.
Phenotropil has some analgesic effect by raising the pain threshold. Also, this drug improves blood flow in the vessels of the lower extremities. On the positive properties of Phenotropil is the lack of teratogenic, carcinogenic, mutagenic, embryotoxic influence and low toxicity.
During the course of taking the drug were observed withdrawal phenomena that reinforces positive feedback Fenotropile. Moreover, not develop tolerance and dependence to the drug dosage. Phenotropil - a patented drug. Analogues Phenotropil yet.
When taken orally, the drug is rapidly absorbed from the gastrointestinal tract, it penetrates the blood-brain barrier. The maximum concentration achieved one hour after ingestion. Do not metabolized in the body. The half-life - 3-5 hours. 60% of the drug is excreted in the bile, and then, 40% - with urine. Characterized by 100% bioavailability Phenotropil.
The instructions to Fenotropilu listed are the indications:
- neurotic condition characterized by deterioration psihodvigatelnoy activity, excessive fatigue, weakness, memory loss, cognitive impairment;
- pathology of the central nervous system associated with a metabolic disorder in the brain and blood circulation, as well as other diseases associated with impaired intellectual and mnemonic functions;
- convulsive disease;
- the need to invert the sleep-wakefulness (in connection with professional activities);
- alimentary and constitutive obesity;
- Schizophrenia (vyaloapaticheskih over);
- prophylactically in stressful situations, extreme effects of professional activities during hypoxia to stimulate mental and physical performance;
- alcoholism (to reduce fatigue, depression, increasing intellectual-mental functions);
- psychoorganic syndrome with symptoms of lethargy, apathy, abulicheskimi disorders.
According to the instructions Fenotropilu, contraindication to the use of the drug - increased sensitivity to individual members of the drug components.
Dosing Phenotropil, dosage
Phenotropil for oral administration. The tablet should be taken after meals. Dosage and duration of treatment is determined by the doctor depending on the clinical situation. Average dose Phenotropil single dose of 100-250mg. The maximum daily dose - 750mg. Recommended daily dosage divided into two steps. If the daily dose is 100 mg, for example single dose per day. The average duration of treatment - a month. When alimentary-constitutional obesity Phenotropil 100-200mg applied for a period of one to two months.
It is advisable to take Phenotropil not later than 15:00.
Phenotropil has a number of side effects: in case of late taking the pill available night insomnia, also noted the appearance of the first three days of treatment of phenomena such as skin redness, psihodvigatelnoe excitement, feeling the tides of heat hypertension.
Application Phenotropil during pregnancy
There were no teratogenic and embryotoxic effect of the drug, however, due to insufficient clinical experience has not recommended the use of Phenotropil during pregnancy and lactation. Due to the same reason Phenotropil not applicable in pediatrics.
Interaction with other drugs Phenotropil
Phenotropil potentiates the effect of anxiolytics and means that excite the central nervous system.
Due to the high activity of the drug Fenotropile positive reviews from both the patients and by doctors. Patients say quite easily portable Phenotropil. Indications for use of the drug is quite extensive, and a variety of pharmacological effects makes it possible to achieve the desired clinical outcome.
Currently, there are no analogues Phenotropil.
In chronic stress, fatigue, significant psycho-emotional exhaustion may increase the body's need to sleep in the first days receive Phenotropil. In such cases, use of the drug is recommended to start at the weekend. Precautions should be prescribed Phenotropil in atherosclerosis, liver disease, kidney disease, the presence of panic attacks in history, during the acute psychotic state, and with a history of allergy to other nootropics.
Before using this drug should be familiar with the instructions to Fenotropilu.
The use of the drug is possible only on prescription.