Pentoxifylline

 Pentoxifylline 100 mg

Pentoxifylline - for the treatment of cardiovascular diseases.

Pharmacological action

Pentoxifylline - the drug from the group angioprotectors. It improves the microcirculation, prevents adhesion of erythrocytes, platelets, has a slight vasodilator effect saturates tissues with oxygen, especially in the legs, arms and the central nervous system, vascular resistance and decreases blood viscosity.

Reviews of pentoxifylline in patients with intermittent claudication confirm that the drug makes it possible to increase the distance by foot, eliminates night cramps, leg pain at rest.

Product form

Pentoxifylline is produced in the form of pills, tablets and conventional long-acting, as a solution for infusions and injections.

Indications pentoxifylline

Pentoxifylline is indicated for cerebrovascular disease, particularly in patients who have had a heart attack or suffering from atherosclerosis of the brain; in violation of the peripheral circulation; chronic or acute insufficiency of blood supply vessels in the eye; nefroangiopatii diabetic.

Another indication for pentoxifylline is functional hearing loss associated with the vascular pathologies.

There is experience with Pentoxifylline during pregnancy - treatment and prevention of placental insufficiency.

Pentoxifylline Guide: how to use

Tablets are taken three times a day for two Bean 0, 1 year After the desired therapeutic effect is achieved, the dosage can be reduced to 0, 3 g - three pills per day. Reduce the dose after an average of one or two weeks.

In general, treatment of pentoxifylline on indications specified in the instruction lasts for about a month - two or three weeks.

In the vein or artery of Pentoxifylline instructions introduced with acute circulatory disorders of the brain or peripheral circulation. In the vein type 0, 1 g of pentoxifylline, a drug is diluted in 250-500 ml of glucose solution or sodium chloride. The infusion lasts for 90-180 minutes. During treatment, the dose may be increased to 0, 2-0, 3 years

The artery drug early treatment is administered at a dosage of 0, 1 g, it was dissolved in 25-50 ml of sodium chloride. Thereafter the treatment is continued by introducing 0, 2-0, 3 g of pentoxifylline, diluted in 35-50 ml of solvent. Agent is administered intraarterially at speed 0, 1 g per 10 minutes.

The dosage Pentoxifylline during pregnancy is calculated individually. Take the drug to pregnant women on their own is not recommended.

side effects

 Pentoxifylline ampoule

There are reviews of pentoxifylline, causes nervousness, insomnia, drowsiness, headache, arrhythmia, nausea, intestinal atony, vomiting, aggravation cholecystitis, stenokardicheskie attack, tachycardia, increased concentrations of liver enzymes, swelling, redness of the skin, leukopenia, bleeding, urticaria, pancytopenia .

When intraarterial or intravenous injection can significantly reduce blood pressure.

Contraindications

Pentoxifylline under the instruction is contraindicated in acute myocardial infarction, heavy bleeding, hemorrhagic stroke, bleeding in the eye.

When cerebral atherosclerosis and coronary vessels can not enter the drug into the aorta.

Due to the fact that the use of Pentoxifylline during pregnancy has not been studied in detail, this condition is considered to be a contraindication for prescription drugs as well as breastfeeding. But as the experience of the use of drugs, it does not cause developmental disorders and malformations in the fetus, so gynecologists consider it possible Pentoxifylline for placental insufficiency in pregnant women.

Children under 12 years can not prescribe medication.

In the appointment of treatment takes into account that Pentoxifylline enhances the effect of high blood pressure medicines, and hypoglycemic effect of insulin.

Judging by the reviews of pentoxifylline, the risk of bleeding is increased with concomitant administration of drugs with ketorolac and meloxicam.

The probability of side effects is increased when combined with the drug cimetidine.





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