Panangin - drug filling shortage in the body of potassium and magnesium.
The main active ingredients Pananginum - magnesium aspartate, and potassium aspartate.
Magnesium and potassium - is intracellular cations play an important role in the interaction of intracellular structures and macromolecules, in the functioning of many enzymes and the mechanism of muscle contraction. Low levels of these ions in the internal environment can cause metabolic changes in the myocardium have proaritmogennoe action (cause arrhythmia), lead to the development of hypertension.
Aspartate, not only is a carrier of magnesium and potassium, but also contributes to their entry into the intracellular space.
The combination of magnesium and potassium ions in the formulation Panangin is because the shortage of potassium in the body, usually also accompanied by a magnesium deficiency, and therefore the content of these ions correction requires simultaneous.
Pananginum produced in the form:
- tablets, film-coated, 50 pcs. in bottles packed in cardboard boxes;
- solution for intravenous administration at 5 ampules (10 ml) in a contour plastic containers that are packaged in cardboard boxes.
The instructions contain the following indications for Pananginum:
- post-myocardial infarction;
- cardiac arrhythmia (in the complex therapy);
- chronic heart disease;
- treatment of cardiac glycosides (in the complex therapy);
- replacement therapy with a deficiency of potassium / magnesium.
According to the instructions, in the form of tablets Panangin contraindicated purpose in such diseases and conditions, such as:
- the metabolism of amino acids;
- AV-blockade of I degree;
- myasthenia gravis;
- Acute metabolic acidosis;
Not assigned Panangin oral and as / in infusion at the following diseases and conditions:
- acute and chronic renal failure;
- AV-block II and III;
- cardiogenic shock (BP & lt; 90 mm Hg);
- Addison's disease;
- hypersensitivity to the drug.
Be wary appoint Panangin for use inside during pregnancy and lactation, intravenously - with AV-blockade of I degree.
Instructions Pananginum: Dosage and Administration
Tablets prescribed to 1-2 pieces. three times a day. Take them follows only after a meal (due to the fact that the acidic stomach environment, reduces the effectiveness of the drug).
The maximum daily dose should not exceed 9 tablets, ie, 3 tablets three times a day.
The duration of treatment and the need for repeated courses of therapy is determined by the attending physician on an individual basis taking into account the indications Pananginum.
The solution is administered intravenously. A single dose of 1-2 ampoules. To prepare the infusion solution contents of the ampoules are dissolved in 5% glucose solution (50-100 ml).
If necessary, re-introduction is possible after 4-6 hours.
With an overdose of pills may impair cardiac conduction, with an overdose of sodium may develop hyperkalemia and gipermagniemiya. In such cases, you should stop taking Pananginum and spend symptomatic therapy, and perhaps even hemodialysis.
Side effects from the use of Pananginum
Panangin, patient testimonials confirm this can cause some side effects.
When administered by rapid intravenous possible development of symptoms gipermagniemii and / or hyperkalemia.
According to the reviews of Pananginum, pills can cause:
- of the cardiovascular system: blood pressure reduction, paradoxical reaction, AV-blockade;
- the central nervous and peripheral nervous system: paresthesia, cramps, hyporeflexia;
- Gastrointestinal: vomiting, nausea, diarrhea, discomfort in the area of the pancreas;
- Respiratory system: respiratory depression.
Application Pananginum possible only on prescription.
Panangin, reviews confirm it does not affect the ability to drive and engage in any activities that require speed of psychomotor reactions and concentration.
Storage and supply of pharmacies
Panangin Tablets are sold in pharmacies without a prescription, the solution is - strictly on prescription.
Keep the drug should be protected from the sun at a temperature of 15-30
Shelf life of tablets is 5 years, the solution - 3 years.