Nitroglycerine

 Nitroglycerin tablets
 Nitroglycerin - a means of improving blood circulation.

Pharmacological action

Nitroglycerin is expanding heart arteries and blood vessels of the brain, has a relaxing effect on the smooth muscle of the gastrointestinal tract, biliary tract and other internal organs.

Application Nitroglycerin helps reduce the level of venous return of blood to the heart, redistribution of it in the heart muscle, which increases myocardial contraction and helps reduce the amount of myocardial ischemic lesions.

Product form

Releasing nitroglycerin in tablets, capsules, solutions, in the form of a patch.

Indications Nitroglycerin

Nitroglycerin is used for instructions to remove stenokardicheskie attacks, for the treatment of mobility ducts, excretory bile.

Nitroglycerine is also possible to use in the central retinal artery occlusion, left ventricular failure, including myocardial.

Dosing Nitroglycerin

The drug is administered orally, intravenously, dermally, sublingually.

Nitroglycerin for angina indication take sublingual (tablet or capsule is placed under the tongue) immediately after the onset of pain - 0. 5-1mg at once. To speed up the effect of the drug can be crushed capsule teeth and take the tool again - after 30-40min.

If the attack after five minutes is not stopped, it is possible to adopt another 0, 5mg means, but if after two or three nitroglycerin tablets therapeutic effect is still missing, you need to seek medical help.

For the prevention of angina nitroglycerin tablets taken orally: in mild cases - one or two tablets of 2 2-3r 9mg / day; in severe cases - one or two tablets of 5, 2-3r 2mg / day. Permissible daily dose - 34, 8 mg

Sublingual Nitroglycerin solution for instructions to stop an attack of angina by taking 1-2kap, keep the mouth until resorption.

 Nitroglycerin solution
 Nitroglycerin indication of chronic heart failure should be used only in hospital

Intravenously administered nitroglycerin diluted in glucose or isotonic 0, 005mg / min, increasing the dosage to 0, 005mg / min every 3-5min.

Nitroglycerin patch glued to the skin 12-14ch.

side effects

Nitroglycerin can cause headache, weakness, anxiety, blurred vision, dizziness, worsening of glaucoma, palpitations, collapse, drop in pressure, redness and blueness of the skin, nausea, diarrhea, vomiting, dry mouth.

Also, the use of nitroglycerin may cause allergic reactions: burning, itching. Because of the use of the patch may develop contact dermatitis.

Nitroglycerin overdose accompanied by: extreme fatigue, dizziness, fainting, chills or fever, sweating, increased intracranial pressure, shortness of breath, blue hands, nails, lips. Also, there is a weak and rapid pulse, high temperature, low pressure. To avoid overdose Nitroglycerin should follow the assigned dosing means. To eliminate the effects of an overdose victim is required to be converted into a horizontal position, his stomach wash, enter the blood plasma substitute, phenylephrine. With an overdose of nitroglycerin can not be administered epinephrine, because may develop shock-like reaction. In some cases, use of oxygen, is introduced a solution of methylene blue - 1-2mg / kg intravenously.

Contraindications

Nitroglycerin is contraindicated according to the instructions in the presence of bleeding in the brain, with increased intracranial pressure, reduced pressure, angle-closure glaucoma, hypersensitivity, collapse, bradycardia, cerebral ischemia, head trauma, pregnancy, lactation.

Nitroglycerin is not indicated by indications myocardial low diastolic pressure in the left ventricle and right ventricular infarction.





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