Nebilet - hypertensive medication with vasodilating properties, used in hypertension, and some diseases of the cardiovascular system.
The active substance of Nebilet has antianginal, anti-ischemic and antihypertensive effect.
The drug is effective in reducing blood pressure, heart rate and total peripheral vascular resistance. The antihypertensive effect of Nebilet Review has a number of advantages compared with other drugs:
- Smooth and physiological reduction in systolic and diastolic blood pressure;
- The absence of a sharp withdrawal discontinuation;
- Lack of resistance to nebilet long-term use;
- The efficacy does not depend on sex, age, and mealtime.
Also according to the instructions Nebilet has cardioprotective and angioprotective effect manifests itself as a normalization of the basal vascular tone, improved extensibility of the arteries and inhibition of the progression of atherosclerosis.
Nebilet produced in the form of white circular tablets with a cruciform notch containing 5 mg of active substance. 7 and 14 tablets per blister.
Produces various analogues Nebilet containing the same active ingredient. These include pills Binelol, Nebivator, Nebivolol-Chaykafarma, Nebikor Adifarm, Nebilong, Nevotenz, OD-Neb, Nebivolol, Nebivolol STADA, Nebivolol, Teva, Nebilan Lannaher. These preparations also contain 5 mg of active substance. Produce and other analogues of Nebilet, similar in therapeutic effect, but differ in chemical composition.
Indications for use of Nebilet
According to the instructions Nebilet is used in:
- Chronic heart failure, often in combination therapy;
- Coronary heart disease.
Nebilet contraindicated to apply at:
- AV-block II and III;
- Severe arterial hypotension;
- Cardiogenic shock;
- Myasthenia gravis;
- Congestive heart failure and chronic cardiac decompensation;
- Pheochromocytoma, without the simultaneous use of alpha-blockers;
- Sick sinus syndrome, including sinoatrial block;
- Metabolic acidosis;
- Severe hepatic impairment;
- Intolerance or lactase deficiency and galactose malabsorption syndrome;
- Bronchospasm and bronchial asthma in history;
- Severe occlusive peripheral vascular disease;
- Hypersensitivity to the active substance - Nebivolol or other components of the drug.
When pregnancy Nebilet is used only on strict conditions and under the control of the utero-placental blood flow and fetal growth. In this use of the drug should be abolished no later than two days before delivery. At the time of application Nebilet breastfeeding to be interrupted. Nebilet on instructions do not apply to the age of 18 years due to a lack of research on efficacy and safety.
Caution should be used when Nebilet tablets hyperthyroidism, psoriasis, renal failure, diabetes, AV-blockade of I degree, chronic obstructive pulmonary disease, allergic diseases, Prinzmetal angina, as well as over the age of 75 years.
Instructions for use of Nebilet
Tablets Nebilet recommended taken once a day, regardless of the meal and the time of day, but preferably at the same time.
For the treatment of hypertension and coronary heart disease usually prescribed daily dose of 2 mg Nebilet 5-5, wherein the preparation can be applied both in monotherapy and in combination with other agents that reduce blood pressure.
In renal failure, and at the age of 65 years, the initial dose should not exceed 1, 5 mg. With good tolerability gradually at intervals of 1-2 weeks, the dose may be increased to two tablets per day Nebilet.
Before using the analog Nebilet must always consult with a physician.
With an overdose of the drug may reduce blood pressure, vomiting, bronchospasm, nausea, cyanosis, AV-block, loss of consciousness, sinus bradycardia, cardiogenic shock, coma and cardiac arrest.
Nebilet used with caution with many drugs because of the potential gain of side effects and changes in the therapeutic effect.
In the opinion of Nebilet often cause headaches and dizziness, diarrhea, increased weakness, constipation and nausea, fatigue, paresthesia.
Much less when using Nebilet tablets may occur: dyspepsia, flatulence, nightmares, vomiting, skin rash erythematous character, bradycardia, depression, AV-block, orthostatic hypotension, congestive heart failure, Raynaud's syndrome, pruritus, bronchospasm, confusion.
Fainting, hallucinations, worsening of current psoriasis, angioneurotic edema, and dryness of the eyes of Nebilet reviews is only in rare cases.
Nebilet - Prescription drug. Shelf life - 3 years.