Motilium - a drug for the treatment of gastrointestinal diseases
Motilium is a stimulator of intestinal peristalsis, has antiemetic effect.
The active substance Motilium - Domperidone, which is characteristic of the effect of some antipsychotic drugs, but unlike them it does not cause extrapyramidal side effects (parkinsonism, dystonia, tremor, chorea, athetosis, akathisia, teak, myoclonus, stereotypes). Also found that increases prolactin domperidone (a peptide hormone that stimulates milk production).
Motilium tone and increases the pressure on the lower esophagus sphincter. In the production of gastric juice the drug has no effect.
Release tablets ordinary lingual (resorption), Motilium suspension.
Motilium is prescribed according to the instructions at: dyspeptic disorders caused by slow gastric emptying, gastroesophageal reflux disease, esophagitis (vomiting, flatulence, feeling of fullness and bloating, belching, heartburn, nausea, epigastric pain), nausea, vomiting, triggered by the use of dopamine agonists patients with Parkinson's disease (such as L-dopa, bromocriptine), nausea and vomiting organic, infectious, functional origin, nausea and vomiting caused by radiation therapy, a violation of the diet, drug therapy.
Motilium is effective for children - cyclic vomiting syndrome, vomiting, gastro-esophageal reflux, gastric motility disorders of other children.
Motilium under the instruction does not apply when: gastrointestinal perforation, obstruction of its mechanical nature, with pituitary tumors, produce prolactin, in the gastro-intestinal bleeding, in case of hypersensitivity to the active and auxiliary substances of the drug.
For these indications Motilium should not be used simultaneously with ketoconazole, erythromycin, voriconazole, fluconazole, amiodarone, clarithromycin, telithromycin.
During lactation, pregnancy is not recommended to use the drug.
Instructions for use Motilium
Motilium for children weighing 35 kg or more is prescribed in the form of coated tablets.
Motilium sublingual tablets on the testimony given in the instructions given only after 5L children, adults.
Motilium is a suspension for children under 5 yrs.
Motilium indication of dyspeptic disorders, children and adults take for 15-30min before meals for three 10mg p / day. Permissible dose - 80 mg / day. 12l after children, adults allowed double the dose, if necessary.
Motilium suspension is received from the rate of 2, 5 ml to 10 kg baby weight. Doubling the dosage can be for children only after a year. Permissible dosage - 2, 4 mg / kg / day, but not more than 80mg / day.
For the treatment of vomiting and nausea adult children after 12l. Motilium is prescribed according to the instructions to take in the volume of 20mg 3-4r / day. before meals, sleeping. Permissible dose - 80 mg / day. Babies 5-12l. 3-4r give 10mg / day. The dosage of the suspension is calculated as follows: 5 ml / 10 kg of weight, take before meals, before going to bed (3-4r / day). Permissible dose - 2, 4 mg / kg / day, no more than 80mg.
Application motilium patients with renal insufficiency is shown to hold with longer time intervals. Correct dosage is not necessary. If necessary re-appointment, the multiplicity of use Motilium reduced to 1-2r / day, with the dosage can also be decreased.
Motilium may cause amenorrhea, hyperprolactinemia (a disease in which increased levels of prolactin), gynecomastia, reversible extrapyramidal pathology at children (run after canceling means), disorders of the gastrointestinal tract, spastic bowel reduction, allergic reactions.
In children under one year Motilium can cause neurological disorders.
Overdose may cause disorientation, drowsiness, extrapyramidal disorder (most often occur in children). For the treatment of extrapyramidal disorders may be assigned anticholinergic agents, drugs to treat Parkinson's disease. Begin to eliminate the symptoms of an overdose with the procedure gastric lavage.