Monosan - vasodilator.
Pharmacological action Monosana
Monosan dilates blood vessels of the brain, reduces preload and afterload on the heart, promotes coronary blood flow diversion in areas where blood flow is reduced, reducing the pressure in the "small" circle of blood and the amount of blood flowing to the right atrium, increases physical endurance patients suffering from angina pectoris, ischemia .
The active substance Monosana - isosorbide mononitrate.
Analogs Monosana - drugs Mono Mac Monocinque administered, Pektrol, Monizol, Monolong.
Monosan prescribed for chronic heart failure, "pulmonary" heart, increased pressure in the "small" circle of blood circulation, peripheral artery spasm: angiospastic occlusive disease and retinitis.
The drug can be used for the prevention of angina pectoris.
Instructions Monosana: how to use
Capsules or tablets Monosan taken one hour before meals or two hours after. Chew the capsules and tablets are not recommended.
At the beginning of therapy administered to a patient take 10-20 mg two times a day, if tablets are used intermediate-acting, and 40-50 mg 1 time per day when applied depot tablets or capsules retard - dosage forms with prolonged effect.
According to the instructions Monosana the third or fourth day of treatment the dosage can be increased up to 20-40 mg. The multiplicity of drug administration - twice a day.
If necessary, the daily dose is increased to 60-80 mg. The maximum daily dose - 80 mg.
Side effects Monosana
Due to the application may Monosana blush facial skin, begin dizziness, tachycardia, headache, nausea, can lower blood pressure, appear dry mouth, burning sensation on the tongue. In some cases, patients may notice increased stenokardicheskie attacks.
There is evidence that treatment with the drug may experience drowsiness, stiffness, blurred vision, skin rash.
Overdose symptoms Monosana: headache, collapse, blurred vision, fainting, hyperthermia, sweating, diarrhea, vomiting, cramps, dyspnea, skin redness, paralysis, bradycardia, coma, increased intracranial pressure. For the treatment of stomach is washed with a solution of methylthioninium chloride, hemodialysis, oxygen therapy, blood transfusions. If there is a marked reduction in pressure, the patient intravenous phenylephrine.
The same side effects cause Monosana counterparts.
According to the instructions Monosan contraindicated in case of intolerance to existing drug substances and excipients, as well as children, pregnant or nursing women.
Under the supervision to take medication in hemorrhagic stroke, acute myocardial infarction, glaucoma, hyperthyroidism, liver failure, low blood pressure, severe anemia, severe renal insufficiency.
Dosage forms with prolonged action Monosana contraindicated in malabsorption syndrome, increased gastrointestinal motility.
During the appointment is considered that isosorbide mononitrate reduces the effectiveness of drugs with vasoconstrictor effect.
Monosana hypotensive effect is enhanced when combined with neuroleptics, ethanol, tricyclic antidepressants, quinidine, procainamide, sildenafil.