Mexidol

M  Mexidol solution
 eksidol - antioxidant drug used to improve brain metabolism and blood supply to the brain, for the relief of withdrawal symptoms and acute purulent inflammation of the abdominal cavity.

Pharmacological action

Mexidol has antioxidant (protects cells from excessive oxidation) of membrane (lipids helps restore cell membranes), antihypoxic (enhances portability tissues or organisms in general, lack of oxygen), nootropic (has activating effect on mental performance, memory, learning ability), anxiolytic (selectively suppresses the feelings of fear, worry, anxiety), anticonvulsant, and lipid-lowering (regulates cholesterol) properties.

Application Mexidol enhances the body's resistance to stress and other damaging effects of factors, which include ischemia, hypoxia, shock, alcohol intoxication, violation of cerebral circulation.

As the reviews, Mexidol included in the complex treatment of patients who have suffered an acute form of cerebral circulation, sposobstvovuet reduce the symptoms of ischemic stroke and increase resistance to hypoxia.

Application Mexidol in acute pancreatitis reduces endogenous intoxication.

The drug helps ease the toxic effect of alcohol and antipsychotics as well as to arrest the acute opiate withdrawal syndrome.

Indications Mexidol

Mexidol instructions recommended for:

  • acute stroke;
  • neurocirculatory and vascular dystonia;
  • vascular encephalopathy;
  • atherosclerotic disorders of the brain;
  • anxiety disorders accompanying neurosis and neurotic condition;
  • acute intoxication with neuroleptics;
  • withdrawal syndrome in alcoholism, when the clinical picture is dominated by neurotic disorders and vegetovascular;
  • acute purulent inflammation of the abdominal cavity (peritonitis, pancreatic necrosis, pancreatitis);
  • conditions involving tissue hypoxia;
  • exposure to extreme factors.

Contraindications

Mexidol not indicated for acute renal dysfunction and liver, as well as in case of hypersensitivity to the drug.

During pregnancy and lactation apply Mexidol statement is not recommended because clinical studies confirming the safety of the drug have been conducted.

Instructions for use Mexidol

Meksidol readings determined range dosage forms, available as a tablet containing 125 mg oksimetiletilpiridina succinate, as well as a solution for injection, 1 ml of which contains 50 mg of active substance.

Mexidol tablets are for oral use. The therapeutic dose and duration of use Mexidol determined by the physician based on the patient's sensitivity to the drug.

In most cases, drug treatment begins with an amount equal to 125-250 mg (1-2 tablets Meksidol), gradually increasing the dose until until a desired effect. The day should not take more than 6 tablets (800 mg). Typically, tablets Meksidol take 2-6 weeks. When relief of withdrawal symptoms accompanying the alcoholism, the drug is recommended to take for 5-7 days. Application Mexidol should be stopped gradually, reducing the amount of the drug for 2-3 days.

 Mexidol pills
 The solution Mexidol, indications the mode of application, can be administered intramuscularly or intravenously. Infusion administration method involves dilution of the drug in an isotonic solution of NaCl. The jet injection of the drug should be slow - at least 5-7 minutes to drip the recommended rate of administration of 40-60 drops per minute.

Despite the evidence, Mexidol daily dose should not be more than 1200 mg.

Treatment of stroke is made as follows: the first 10-14 days 2-4 times a day for 200-500 mg, administered intravenously; 14 days later - 2-3 times a day for 200-250 mg to be administered intramuscularly. The scheme of the use of the drug reviews Mexidol characterized as effective.

Side effects

Adverse effects of the drug Mexidol reviews and instructions are dry mouth, nausea, allergic reactions.

Additional Information

According to the instructions, Mexidol does not require special storage conditions, enough dark, dry place where the temperature does not rise above 25 0 C. Compliance with this condition will help to save Mexidol therapeutic properties for three years.





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