Melbek - anti-inflammatory drug.
Melbek - a non-steroidal drug, whose active ingredient - meloxicam.
The drug has antipyretic, analgesic, anti-inflammatory effect.
Established that Melbek has less toxicity than other anti-inflammatory drugs nesteroidov group (for example, diclofenac, naproxen, piroxicam), which may have a negative effect on the kidneys and the digestive system.
It is also observed that Melbek at recommended doses has no effect on platelet aggregation, bleeding time whereas naproxen, ibuprofen, diclofenac, indomethacin significantly prolong bleeding time and inhibit platelet aggregation.
MELBEK active substance is rapidly absorbed from the digestive tract, regardless of meal times, the maximum concentration in the blood reaches across 5-6ch after internal use. The uniform concentration of resources occurs through 3-5sut. therapy.
In intramuscular meloxicam is completely absorbed, the maximum concentration of up to one hour after injection Melbek.
Melbek release tablets, solution for injections Melbek and rectal suppositories.
The instructions Melbek indicated that the drug is indicated for the symptomatic treatment of rheumatoid arthritis, for the relief of pain in osteoarthritis, degenerative joint disease, osteoarthritis, ankylosing spondylitis, relief of pain of various origins (toothache, pain after injury or surgery, the pain of dorsalgia, myalgia, algodismenoree, sciatica).
Instructions for use Melbek
Tablets Melbek recommend be taken with food, they can not chew. The recommended dose - 7 5-15mg one p / day.
Intramuscular injections Melbek do only in the first few days of treatment, and then go on the pill.
Combining combination therapy injections and pills Melbek not exceed the daily dose of 15 mg.
Rectal suppositories Melbek administered one p / night for one thing (15mg).
Patients on hemodialysis who suffer from renal insufficiency, should not take more than 7, 5 mg of the drug / day.
Patients who are at increased risk of side effects, begin treatment with 7, 5 mg / day.
Correct dosage Melbek for patients with mild, moderate renal disease, cirrhosis of the liver in the compensated stage is not required.
Melbek can cause vomiting, diarrhea, nausea, constipation, flatulence, esophagitis, hepatitis, abdominal pain, gastritis, colitis, may trigger the development of gastroduodenal ulcers, impaired vision, conjunctivitis, swelling, angioedema, acute renal failure, stomatitis, rash, itching, irritation, skin, anemia.
Also instructions Melbek stated that it can cause an increase in the level of transaminases, bilirubin, creatinine, changes in blood count (cytopenia, thrombocytopenia, leukopenia), headache, dizziness, fatigue, mood changes, tinnitus, edema, increased pressure.
Melbek of instruction is contraindicated in: renal failure, hepatic, hypersensitivity, peptic ulcer dvenadatsatiperstnoy gastrointestinal tract in the acute phase, bronchial asthma, nasal polyposis, angionevroticheskom edema, urticaria caused by the use of acetylsalicylic acid and other nonsteroidal anti-inflammatory drugs. Nor can we accept funds nursing, pregnant women, children up to 15L.
Melbek intravenous injections do not.
Do not take a combination of two or more non-steroidal drug, because high probability of bleeding from the gastrointestinal tract, it ulcers. It should also be borne in mind that Melbek desirable to combine with lithium salts (nesteroidy inhibit the process of removing lithium salts by the kidneys, which leads to their accumulation and toxicity). Preparations tend to exacerbate the effects of ticlopidine, heparin, because of which increases the risk of bleeding from the stomach opening.
Women who use contraceptive IUD for, keep in mind that Melbek reduces its effectiveness.
Applying medication with diuretics simultaneously, it is necessary to use a sufficient amount of liquid.
It is also known that meloxicam reduces the effectiveness of drugs that lower blood pressure.
Not to be combined with cyclosporine Melbek since This can cause nephrotoxic effect of the latter.
No information on the possibility of combining the drug with antacids, digoxin, furosemide, so you should seek professional advice before starting therapy.
Permission is granted to use Melbek with oral antidiabetic drugs.