Logest

Logest - low-dose monophasic combined oral contraceptive.

Structure and Composition

 Logest
 Logest produced in the form of tablets with a white shell. Each tablet contains 0, 075 mg gestodene and 0, 02 mg of ethinyl estradiol. Also includes auxiliary components: lactose monohydrate, corn starch, talc, magnesium stearate, polyvidone, sucrose, macrogol, calcium carbonate, carnauba wax.

According to the instructions Logest in one package contained 21 tablets of the drug and polyvinyl chloride blister. The box may be 1 or 3 blisters with instruction and a calendar treatment.

Pharmacological action Logest

According to the instructions, Logest has a contraceptive effect. This drug combination (containing estrogen and progestogen) and its effect is caused by three mechanisms. Firstly, Logest suppresses ovulation at the hypothalamo-pituitary level. Secondly, the drug alters the viscosity of cervical mucus, resulting in sperm can not penetrate into the uterine cavity. Logest also affects the condition of the endometrium by inhibiting the implantation of the egg.

Women taking combined oral contraceptives have a regular menstrual cycle, less painful and intense menstruation. There is also information about reducing the risk of ovarian cancer in women taking oral contraceptives.

After receiving instructions on Logest gestodene and ethinyl estradiol are rapidly absorbed, the maximum concentration in the blood is determined through a 1-1, 7:00 after taking the drug. Bioavailability - 99% and 45% respectively. In the opinion of Logest, it is a modern and reliable contraceptive.

Indications

Application Logest shown for contraception in women of childbearing age.

Contraindications Logest

Application Logest contraindicated in these situations:

  • arterial and venous thrombosis and thromboembolism, including myocardial infarction and stroke (in the present or past);
  • states which are the precursors of Thrombosis (angina, transient ischemic attack);
  • expressed risk factors (or multiple) of thrombotic events (for example, cardiac arrhythmias, valvular apparatus injury, uncontrolled hypertension);
  • diabetes (including microangiopathy);
  • migraine, focal neurological symptoms in history;
  • pancreatitis with lipid disorders (now or in history);
  • severe liver disease, liver failure (increased transaminase levels);
  • tumors of the liver (now or in history);
  • hormone-dependent malignancies (breast, genitals), including suspected them;
  • uterine bleeding of unspecified origin;
  • pregnancy and lactation;
  • hypersensitivity to the components Logest;
  • surgical surgery of the lower limbs, prolonged immobilization, extensive traumatic injuries.

In the event that any of these conditions develops during treatment with Logest, the drug should be lifted immediately.

Precautions Logest used for lipid disorders (hyperlipidemia, obesity and others.), In otosclerosis with hearing loss, jaundice of unknown origin or congenital hyperbilirubinemia (Gilbert's disease, rotors, etc..) And systemic lupus erythematosus, Crohn's disease, anemia, hypertension.

Admission during pregnancy and lactation

According to the instructions, Logest should not be used during pregnancy and lactation. In case pregnancy occurs while taking the drug, he immediately canceled. The clinical studies did not reveal any adverse effects on the fetus Logest and development pregnancy.

The reception of the drug during lactation may affect the quantity of breast milk and the effect on its composition, so use Logest during lactation is not recommended.

Instructions Logest: Dosage and administration

The tablets of the drug, taken orally in the manner indicated on the packaging, in the same time, with a little water. It continuously receive Logest within 21 days. Start taking the next pack should be after the 7-day break (during which is usually marked by bleeding). Usually bleeding starts on day 2-3 after the last tablet Logest, it can last more than 7 days.

Start receiving Logest of instructions should be on the first day of the menstrual cycle (ie the first day of menstruation), if you have not used drugs in the past month, some - or hormonal contraceptives. You can receive Logest in the first 2-5 days of the menstrual cycle, but it is recommended to use an additional barrier method of contraception during the first week of treatment.

In that case, if you take other combined hormonal contraceptives, it is recommended to switch to Logest immediately after the last tablet previous (for products designed for 28 days), or immediately after the 7 day interval (for products designed for 21 days).

If you are taking medications that contain only progestin ("mini-pill"), or you had intrauterine device (eg, Mirena), then go to Logest possible on any day after the reception of these funds (or remove helix). In any case, additional barrier method of contraception in the first week of admission Logest.

After an abortion in the first trimester (12 weeks) to take the drug Logest possible any day (including immediately).

In case of missed pills Logest should take it as soon as possible. If the delay is less than 12 hours, the contraceptive protection is not affected. If the delay in receiving more than 12 hours, the contraceptive protection is reduced.  Logest pills

Overdose

In overdose Logest may experience symptoms of nausea, vomiting, bleeding from the genital tract, uterine bleeding. There is no specific antidote. Treatment is symptomatic.

Side effects Logest

Side effects Logest can be expressed as follows: stress and breast tenderness, spotting from the genital tract, discharge from the breast, decreased libido, headache, mood changes, nausea, vomiting, poor tolerance of contact lenses, skin rash, erythema, pruritus , a change in vaginal secretions, allergic reactions, changes in body weight, cholestatic jaundice, fluid retention.

Occasionally there may be a side effect Logest such as diarrhea and fatigue.

Thrombosis and thromboembolism may in very rare cases.

In the opinion of Logest rarely causes side effects, but if they do occur should consult a doctor.

Interaction with other drugs

When long-term therapy with drugs that induce liver enzymes (phenytoin, barbiturates, carbamazepine, rifampicin, primidone) reduce the risk Logest efficiency, as well as occurrence of uterine bleeding.

Note that while receiving antibacterial drugs (tetracycline, ampicillin) and Logest its contraceptive capacity can be reduced.

Also note that in this medication may require correction hypoglycemic agents and anticoagulants.





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