Levofloxacin

 Levofloxacin Tablets
 Levofloxacin - antimicrobial antibiotic.

Pharmacological action

Levofloxacin is a fluoroquinolone, is considered more effective than ofloxacin due to its formula.

Levofloxacin is active against Haemophilus influenzae, the causative agent of chancroid, Helicobacter akinetobaktera, enterobacteria Escherichia coli, tsitrobakter Freund, some strains, Morganella, Gardnerella vaginalis, Klebsiella, gonorrhea, Proteus, meningococcus, Salmonella, Proteus vulgaris, Pseudomonas, serratsy, streptococcus, staphylococcus , Listeria monocytogenes, enterococci, mycobacteria, mycoplasma, chlamydia, legionella, vartonelly, ureaplasmosis, Moraxela catarrhalis (the causative agent of infections of the upper respiratory tract mucosa), Haemophilus parainfluenzae, Pasteurella spp, Providencia spp

It is also sensitive to the Bacteroides fragilis levofloxacin, Clostridium perfringens, peptostreptokokki, Bifidobacterium, fuzobakterium, Veilonella spp, Propionibacterum spp.

Active substance levofloxacin after internal use is rapidly absorbed from the digestive tract, the magnitude and rate of its absorption is not influenced by food intake.

Product form

Levofloxacin release tablets, infusion solutions.

Analogs of levofloxacin - Tanflomed, Maklevo, Levofloks, Ekolevid, tavanic, Fleksid, Levotek, Lefoktsin, Levolet, Fleksid, Elefoks, Signitsef, Remedy,

Indications Levofloxacin

Levofloxacin is effective for the treatment of infections that occur in the abdominal cavity, exacerbations of chronic bronchitis, acute sinusitis, inflammation of the prostate gland, uncomplicated and complicated urinary tract infections, certain forms of pneumonia, bacteremia, septicemia.

Good reviews of levofloxacin is used to treat infections of the skin and soft tissues.

Contraindications

The instructions given levofloxacin, the drug should not be prescribed if: epilepsy, hypersensitivity pathologies tendon after receiving other fluoroquinolones in the past. The use of levofloxacin is contraindicated for children up to 18L., Nursing women, pregnant women.

There are also reviews of levofloxacin, indicating that caution in the use of antibiotics should be observed in patients with deficiency of glucose-6-phosphate dehydrogenase, geriatric patients with a high risk profile of renal insufficiency.

When you go to analogues of levofloxacin should be borne in mind that drugs may have other contraindications.

Instructions for use of levofloxacin

Levofloxacin Tablets for instructions should be taken before meals, washed down with 0 5-1st.vody, they can not chew.

Infusion of levofloxacin intravenously spend - at 0, 5g two p / day (dosage depending on the patient's condition may change).

For the treatment of chronic bronchitis in acute take 0, 5-0, 25g one p / day per two weeks.

To treat prostatitis take 0, 5g antibiotic one p / d 28d.

For the treatment of complicated urinary tract infections prescribe the use of levofloxacin at a dosage of 0, one p 25g / day. for 7-10dn; uncomplicated - 0, 25g one p / day for three days.

When sinusitis take 0, 5g one p / day. 10d or within two weeks.

In chronic bronchitis take 0, 5-0, 25g one p / day. 1-2ned.

According to the instructions at the beginning of levofloxacin therapy of septicemia, bacteremia spend intravenous infusion, after taking pills - 0, 5-0, 1-2r 25g / day for one, two weeks.

 Lefoktsin - analogue Levofloxacin
 With infections of soft tissue, skin, take 0, 25g one p / day. for one to two weeks or 0, 5g one, two p / day. for 1-2ned.

For the treatment of infections of the abdomen appoint 0, 5-0, 25g one p / day. for 1-2 weeks.

Analogs of levofloxacin used in other dosages, so their appointment can only be done by the doctor.

side effects

Application of Levofloxacin may cause nausea, severe diarrhea, abdominal pain, vomiting, hepatitis, worsening of appetite, drastic reduction of pressure, allergic pneumonitis, vasculitis, swelling of the face, throat, mucous membranes, skin redness, itching, erythema multiforme exudative, Development Stevens-Johnson syndrome, toxic epidermal necrolysis.

There are also reviews of levofloxacin, causes a decrease in the amount of glucose in the blood, increase in liver transaminases, bilirubin, serum creatinine, renal failure acute, sleep disturbance, drowsiness, dizziness, headache, tremor, depression, anxiety, confusion, convulsions , impaired vision, hearing, smell, taste, tactile sensitivity.

Levofloxacin also can lead to injuries and tendon rupture, joint, muscle pain, muscle weakness, hypotension, vascular collapse (rare), tachycardia, agranulocytosis, thrombocytopenia, neutropenia, pancytopenia, hemolytic anemia, a decrease in the number of eosinophils, white blood cells, the development of severe infections.

After the first two days use of levofloxacin may occur bilateral Achilles tendon rupture.

For other side effects include asthenia, fever, appearance of secondary infection, superinfection.





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