Levitra belongs to the category of funds intended for the treatment of erectile dysfunction in men.
International name - Vardenafil.
Basic pharmacological properties and effects on the male body
Because the drug is an inhibitor fosfodiestrady fifth type (PDE5), the use of Levitra allows a high level of effectiveness to treat sexual dysfunction in men. As a result of the treatment restores the ability to achieve and maintain stable erection throughout sexual intercourse. An erection is accompanied by haemodynamic process helps to relax the smooth muscles of the penis cavernous bodies and arterioles which are in it.
The first end of the corpus cavernosum during sexual stimulation begin to secrete nitric oxide (NO). Also, it increases cyclic cGMP (guanosine monophosphate). This helps to relax the corpus cavernosum and the simultaneous increase in blood flow to the penis.
A feature of the drug is its fast absorption. Thus, according to reviews of Levitra, its effect is manifested within 15-25 minutes after ingestion (depending on the individual characteristics of the men). The duration of action is an average of four to five hours after administration.
The use Levitra provides maximum after about 60 minutes (depending on the patient indicator may vary from 30 to 120 minutes).
Reviews of Levitra also confirm the fact that the effectiveness of the drug decreases after eating too greasy food. Thus the drug together with a conventional food has no adverse effect on the pharmacokinetics of the drug.
The composition of the drug and the release form
Levitra is available in the form of tablets of 5, 10 or 20 mg each. Tablets coated. Each package can be from one to twelve tablets.
The active drug substance is vardenafil hydrochloride trihydrate.
Indications for use of Levitra
The drug is indicated for the treatment of erectile dysfunction in men, ie, inability to achieve and / or maintain an erection necessary for satisfactory sexual intercourse full.
Levitra is contraindicated in patients categories to avoid excessive sexual activity among these people:
- undergone no more than 6 months ago, a stroke or myocardial infarction;
- is stable low pressure at rest (less than 90 mm Hg. post);
- characterized by a sharp increase in uncontrolled blood pressure;
- which is peculiar to the unstable nature of angina;
- with the presence of congenital prolongation of the interval QT;
- with different kinds of stenosis;
- renal failure requiring dialysis;
- degenerative diseases of the retina;
- suffering from leukemia, myeloma, anemia;
- with exacerbation of ulcer disease, as well as having a predisposition to bleeding;
- with increased individual sensitivity to the components of Levitra;
- taking HIV protease inhibitors (ritonavir, indinavir);
- taking medications that contain nitrates in its composition.
The drug is not indicated for use in women, children and adolescents under 16 years of age.
Instructions Levitra: how to use and dosage
A method for receiving Levitra - oral, to food intake are not tied.
To obtain the effect of ingestion requires sexual stimulation.
The drug is taken on average 25 minutes - 1 hour before sexual intercourse. The optimal dose is 10 mg. If such dosage gives low efficiency, its dual assigning receiving 20 mg. As a rule, the testimony of an increase in dose are diseases such as diabetes and prostatectomy.
Indications for dose reduction are:
1. The age of the patient.
For men older than 65 years are usually assigned 5 mg of Levitra for the reception. Doubling the dose is possible if the recommended 5 mg did not have the desired effect, but if the higher dose did not have a negative effect on the body (this depends on the individual patient and his sensitivity to the ingredients of Levitra).
2. Violations of the liver wearing moderate. Thus the recommended dose is 5 mg.
3. The course of treatment with other drugs. In this case, the use Levitra limit dose of 2, 5-5 mg.
According to the instructions for Levitra is not recommended to take the drug more than once a day.
The maximum allowable daily dose is 20 mg.
Reviews of Levitra it possible to fix a case of one-time administration of the drug at a dose of 80 mg. No side effects of negative character is not caused. However, the use of two doses of 40 mg for one day contribute to the emergence of highly expressed lower back pain.
If overdose requires symptomatic and supportive therapy.
Side effects of Levitra
Instructions for Levitra lists a number of side effects that can cause drug. These include headaches, blurred vision, dizziness, increased muscle tone, drowsiness.
In rare cases: dyspepsia, nausea, increased GGT (gamma-glutamyl), pain in the lumbar region, rhinitis, laryngeal edema, myalgia, increased creatine kinase.
Since the production of the drug is fit for 3 years.
The optimum temperature for storage of Levitra should not exceed 30 degrees Celsius.