It refers to the group Latran antiemetics. It is a highly effective drug, able to stop vomiting of any origin (including those created as a result of the course of chemotherapy or radiotherapy in the treatment of cancer).
Latran in tablet form is listed in the list of medications "additional drug supply." Decree of the Government of the Russian Federation adopted 29.03.2007, the drug is also included in the "List of Essential Medicines."
The international non-proprietary name Latran - ondansetron.
The active ingredient of the drug is ondansetron hydrochloride dihydrate.
Latran sold in the form of tablets, coated tablets, as well as a solution for administration of injections (intravenous and intramuscular).
Tablets are available:
- contour package comprising two, four or ten tablets (4 mg);
- in canisters of polyethylene, containing two or four tablets;
- orange glass jars weighing 400 g or 800 (respectively, 4000 or 8000 tablets).
The solution enters Latran Pharmacy blister made of PVC film containing one, two or five vials capacity of 2 or 4 ml.
The appointment of the drug Latran is necessary and appropriate to address such manifestations:
• nausea and vomiting caused by chemotherapy effects on the body, radio or radiotherapy;
• nausea and vomiting caused by the intake of anticancer drugs;
• nausea and vomiting due to the negative impact of ionizing radiation;
It is also indicated for the prevention Latran nausea and vomiting after surgery, for the symptomatic treatment of alcohol abstinence syndrome (especially if its severity can be assessed as mild or moderate).
According to the instructions, Latran is contraindicated during pregnancy, lactation and children under two years of age (the drug in Russia has not been tested to determine its safety for this age group).
An obstacle to the appointment of Latran is increased individual sensitivity to the components of the drug.
Instructions Latran: dosage and methods of use
Depending on the nature of vomiting and the overall picture of the disease daily dose Latran can range from 8 to 32 mg. Mode of the drug prescribed on an individual basis by the attending physician.
For elderly the dosage is calculated in the same way as for the other patients.
In cases where there are disorders of the liver, the daily dose can be reduced.
Patients suffering from intestinal obstruction after receiving Latran should be under a doctor's supervision, because the drug may promote the formation of constipation.
Side effects from taking Latran
Instruction Latranu lists a number of side effects that may occur as a result of taking the drug, including headaches, impaired motor function, arrhythmia, pressure drop, disorders of the gastrointestinal tract, allergic manifestations, local reactions.
Possible manifestations of adverse reactions in patients who have individual sensitivity to peers Latran.
In cases of overdose symptomatic therapy is required. Specific antidote to Latranu not available.
Features of use Latran
The solution for injection should be prepared immediately before administration of the drug. The maximum permissible storage time - one day. Permissible storage temperature ranges from 2 to 8 degrees.
Ready solution maintains its properties even when struck by sunlight, so protected from light prior to administration of the drug is required. In the context of the natural / normal light solution properties remain unchanged throughout the day.
Latran is usable for 3 years when stored - protected from the sun spot, the temperature not exceeding 25 degrees.