Korglikon

 Korglikon
 Korglikon - cardiovascular agent.

Pharmacological action

Korglikon - a cardiac glycoside, which is a specific pharmacological effect similar to strophanthin, but has a longer action.

Korglikon increases the speed, the strength of myocardial contraction (positive inotropic effect), systole under its influence becomes shorter, economical energy. Due to the increased contractility miokardnoy minute and stroke volume increases. It is also noted that in patients receiving Korglikon reduced diastolic, systolic volume of the heart, which, together with an increase in cardiac tone decreases myocardial oxygen demand.

When atrial tachyarrhythmia Korglikon slows heart rate, increases the diastole, improves systemic, intracardiac hemodynamics.

After taking the drug, as indicated Korglikon chronic heart failure dilates blood vessels, decreases venous pressure, edema, shortness of breath, increased diuresis.

Product form

Producing Korglikon solution for intravenous administration.

Indications Korglikon

Korglikon of instruction prescribed for atrial tachyarrhythmia, atrial flutter (to reduce the heart rate, atrial flutter in the transfer fibrillation), paroxysmal supraventricular tachycardia, congestive heart failure, chronic, acute left ventricular failure, chronic "pulmonary" heart.

Contraindications

According to the instructions Korglikon not prescribed for: endocarditis, cardiosclerosis expression of acute myocarditis, bradycardia, atrioventricular blockade 2-3y extent of hypertrophic cardiomyopathy, angina unstable, disease Wolff-Parkinson-White syndrome, ventricular tachycardia, cardiac tamponade.

Do not prescribe the drug for children up to 2 years.

Caution should be exercised when administering Korglikon elderly patients, bradycardia, sinus node weakness syndrome, blockade AV, takihardii ventricular paroxysmal, hypertrophic obstructive cardiomyopathy, mitral stenosis, isolated, acute myocardial infarction, unstable angina, heart failure, a chronic pathology of diastolic function, arrhythmia, asthma, heart in patients with mitral stenosis, with dilatation of cardiac cavities, "pulmonary" heart, electrolyte disturbances, alkalosis, obesity, hypothyroidism, hypoxia, myocarditis, arteriovenous shunt.

 Korglikon administered intravenously
 Instructions for use Korglikon

By all indications Korglikon administered intravenously. The solution was 0, 06% injected slowly - for 4-5min to 0, 5-1ml two p / day. Babies 2-5l. administered 0, 2-0, 5 ml, 6-12l. - 0, 5-0, 75ml. Before introduction Korglikon dissolved dextrose or 40% sodium chloride 0, 9% - 10 or 20ml.

Permissible Korglikon single dose intravenous administration - 1ml daily - 2 ml.

side effects

Korglikon can provoke arrythmia, bigeminy, bradycardia, heart rhythm dissociation, the deterioration of the function of the conduction, arrhythmia, blockade of AV.

In addition, the drug can cause vomiting, diarrhea, deterioration of color vision, appetite and sleep, nausea, abdominal pain, drowsiness, allergic, psychosis, delirium, confusion, thrombocytopenia, thrombocytopenic purpura, petechiae, dizziness, nosebleeds, gynecomastia, headache pain.





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