Kolhikum - a remedy for gout.
Under the influence of the formation of white blood cells kolhikum decreases in inflammation, the production of uric acid salts - so realized protivopodagricakih effect of the drug.
It was also established that kolhikum inhibits cell division and prevents the development of amyloidosis.
The high efficiency of the drug observed in acute gout. Significant improvement has been observed in the first 12 hours of treatment (more than 75% of study patients).
In addition, the drug prevents acute attacks of familial Mediterranean fever, positive impact on the life expectancy of patients with primary amyloidosis AL.
In systemic scleroderma due kolhikum marked decrease dryness and skin softening.
The active ingredient of the drug - colchicine contained in the seeds of the autumn colchicum, form the basis of kolhikum.
Kolhikum instructions for use in acute attacks of gout, familial Mediterranean fever.
Instructions kolhikum: how to use
For the relief of acute gouty attack at the beginning of the treatment prescribed 1 mg of colchicine, and after every 1-2h to 0, 5-1, 5 mg until the pain decreases. It is recognized that the daily dosage should not exceed 8 mg. Re-take the drug on a similar scheme can be only three days.
For the prevention of acute gouty attacks take 0, 5-1, 5 mg of the drug every day for three months. It is allowed and the drug every other day. As a preventive measure to combine kolhikum uricosuric agents that increase the excretion of uric acid.
During therapy regularly hematology control to monitor the overall condition of the patient.
Kolhikum may cause pain in the stomach, leukopenia, nausea, diarrhea, vomiting. In some cases, because of the drugs developed neuropathy, myopathy, agranulocytosis, anemia, alopecia.
If the side effects from the gastrointestinal tract increase, decrease the dosage or stop treatment.
Kolhikum not be taken in case of insufficiency of liver / kidney, with marked inhibition of blood in the bone marrow, hypersensitivity, as well as pregnant women, breastfeeding women.
Under the supervision of patients taking the drug in the elderly, those who suffer from cachexia, severe disorders of the gastrointestinal tract, cardiovascular system.
The concentration of media attention is not affected.
Efficiency kolhikum reduce cytostatics. The risk of myopathy is increased when combined with cyclosporine kolhikum, thrombocytopenia or leukopenia causes simultaneous reception nesteroidami drug with other drugs that cause mielodepressiu.