Klarotadin (international medical name - loratadine) belongs to the H-1 histamine blockers, long-acting, aimed at the prevention and treatment of various types of allergic reactions. The drug is effective in the treatment of both seasonal and year-round allergies.
The main active ingredient of the drug - loratadine.
Auxiliary components: sorbitol, sodium benzoate, citric acid, glycerin, propylene glycol, purified water, flavoring flavorings.
Kloratadin available as:
- Syrup in bottles of 100-150 ml,
- Tablets in a package of 10 pieces. 10 mg
- A suspension for oral administration.
Kloratadin acts as a suppressant of leukotriene and histamine release from mast cells, stopping the development of allergic reactions. The drug has a high anti-allergic effect, relieves itching and swelling of tissues, eliminates muscle spasms.
A lot of positive feedback about Kloratadine as an antihistamine no sedative effect and reduces psychomotor functions.
Preparation action begins within 30 minutes after administration and lasts approximately 20-24 hours.
Also good reviews Kloratadin received for the lack of mental decline and anticholinergic action.
The drug is prescribed for a variety of allergic reactions and chronic seasonal types: rhinitis, conjunctivitis, hives, hay fever, dermatitis, angioedema.
It is also used in Kloratadin pseudoallergic reactions provoked by the release of histamine.
Positive feedback on Kloratadin allergy and inflammation of the mucous membranes after insect bites.
Instructions for use Kloratadina
In accordance with the instructions Kloratadin designate adults and children (weighing at least 30 kg): 1 tablet per day. For younger children, having a body weight less than 30 kg, the dose should not exceed 5 mg per day.
Kloratadin has good absorption and rapid therapeutic effect.
When concomitant administration Kloratadina and inducers of microsomal oxidation reduces the effectiveness of the treatment of allergies. In this case, on the recommendation of a doctor daily dose may be increased.
According to the instructions Kloratadin should be taken with caution when driving in dangerous activities and objects that require attention.
Patients with kidney and liver Kloratadina daily dose should be 5 mg.
The main contraindication to receiving Kloratadina is individual intolerance of components.
Precautions should be taken Kloratadin during pregnancy and lactation.
Also not recommended for the drug in renal and liver failure.
In the interaction with CYP3A4 inhibitors Kloratadina CYP2D6 and reduced absorption and efficacy.
Side effects Kloratadina
In adult patients after long-term use of the drug may cause headaches, dizziness, nausea, excessive sweating, aggravation of gastritis, anaphylaxis, allergic reactions, disturbance to the functioning of the liver and kidneys.
Children can appear headaches, nervous excitability, tachycardia, and sleep disorders.
In case of overdose and poisoning Kloratadinom immediately to gastric lavage and take a few pills of activated carbon.