Ketotifen is anti-allergic and anti-asthmatic drug.
Ketotifen is a mast cell stabilizer, which by inhibiting calcium ion current and decrease in their number of mast cells prevents the release of histamine and other mediators of allergy and inflammation.
Application ketotifen reduces the accumulation of eosinophils in the airway, the content of which is increased in allergic conditions, as well as to suppress the early and late asthmatic responses to stimulus.
Ketotifen is able to prevent the development of bronchospasm, but does not have the properties of bronchodilators. After oral administration the maximum concentration of drug in the blood can be observed within 2-4 hours after instillation in the eye quickly ketotifen exhibits its properties, while maintaining antihistaminic effect for 8-12 hours.
The full therapeutic effect of the drug ketotifen, reviews confirm manifested through 1 5-2 months after initiation of treatment.
Use ketotifen instruction recommends to prevent allergic diseases such as allergic bronchitis, atopic (allergic) asthma, allergic rhinitis, hay fever, urticaria, allergic dermatitis, allergic conjunctivitis.
Instructions for use Ketotifen
Syrup, capsules and tablets ketotifen relates to the form of preparations intended for oral administration.
Adults take Ketotifen guide recommends two times a day with meals for 1 mg. If Ketotifen has a soothing effect, treatment should begin with 0, 5 mg at a time, gradually increasing the dose until the desired amount of drug. The maximum daily dose - 4 mg, divided into two prima.
Ketotifen is recommended to give the children as a syrup from six months to three years is prescribed twice a day for 0, 05mg, children older than 3 years, a single dose is doubled.
The minimum duration of the use of ketotifen - 3 months, the abolition of the drug should be made gradually over 14-28 days.
Ketotifen eye drops 0 and 025% was instilled in the conjunctival sac twice a day for one droplet. Eye drops ketotifen children under the age of 12 years shall be imposed. The duration of treatment should not exceed 6 months.
Adverse effects of the drug ketotifen reviews and clinical studies include:
- fatigue, slow reaction rate, dizziness, drowsiness, anxiety;
- constipation, indigestion, vomiting, nausea, increased appetite, dry mouth;
- cystitis (bladder infection), violation of urination;
- weight gain, thrombocytopenia (low platelet counts), allergic skin reactions.
Contraindications to the use of ketotifen
Ketotifen, the use of which must be approved by your doctor if hypersensitivity is not appointed, as well as pregnant and lactating women.
Be wary of ketotifen manual recommends that liver failure and epilepsy.
Ketotifen tablets, capsules, drops and should be stored at a temperature not exceeding 25
C. The syrup should be kept at a temperature corresponding to 5-15
C. With proper storage Ketotifen will fit within 3 years.