Ketosteril a combined preparation for L-amino acids supply the organism and the excretion of metabolic products with nitrogen.
The product is aimed at restoring proper protein anabolism and improve metabolism - nitrogen, potassium, magnesium.
The main active substances are ketone analogues of amino acids:
- α-ketoanalog isoleucine - 67 mg,
- α-ketoanalog leucine - 101 mg
- α-valine ketoanalog - 86 mg,
- α-phenylalanine ketoanalog - 68 mg,
- α-methionine ketoanalog -59 mg.
The composition includes Ketosterila monoacetate lysine, threonine, tryptophan, tyrosine, histidine, nitrogen and calcium.
Excipients are corn starch, magnesium stearate, povidone, macrogol, silicon dioxide, talc.
The shell of each tablet formulation consists of corn starch, talc, methyl methacrylate copolymer, Eudragit E12.5, titanium dioxide and triacetin.
The drug comes in tablet form oblong, film-coated yellow in a carton of 20 pcs.
Pharmacological properties Ketosterila
Ketosteril actively promotes the breakdown and removal of nitrogen substances from the body, thus reducing the amount of magnesium and potassium in the blood.
Positive feedback received Ketosteril as a drug effectively improves kidney function and protein synthesis provides nitrogen. Also Ketosterile ketone analogues of amino acids reduce the synthesis of urea.
The systematic use of the drug in combination therapy in the treatment of renal failure uremic symptoms reduced.
Also good reviews on Ketosteril as a medicine directed to delay dialysis.
Ketosteril indicated for the prevention and treatment of renal failure, disorders of protein metabolism and protein, and in severe malnutrition.
Instructions for use Ketosterila
In accordance with the instructions Ketosteril designate an adult to 3-7 tablets three times a day, children from three years of 1 to 3 tablets a day. The drug should be taken with meals, not liquid, but with a little water.
Also according to the instructions Ketosteril should be applied over a course of treatment with a physician permanent control of phosphate and calcium in the blood.
In Ketosterile ketone analogues of amino acids increases the protein content and normalize the functioning of the kidneys. The protein content should correspond to the degree of kidney function and dialysis before the protein must be determined by diagnostic indicators.
Should regularly monitor and test the calcium phosphate reduction in serum. According to the instructions Ketosterila with a high content of calcium dose should be reduced.
In the treatment of renal failure calorie intake must be regulated, and contain no more than 30-40 grams of protein per day.
The main contraindications to the use of Ketosterila are hypercalcemia and hypersensitivity to the components in the composition of the drug.
Also, do not use the drug in patients with severe violations of amino acid metabolism. Precautions Ketosteril appointed during pregnancy and lactation.
Side effects Ketosterila
In some cases, while taking the drug may occur hypercalcemia.
If the total composition therapy with Ketosterilom prescribers antacid type, then there is a risk of hypophosphatemia.