Ketoconazole

 Ketoconazole tablets

Ketoconazole - antifungal agent.

Pharmacological action

Ketoconazole affects the system, superficial fungal infections.

Effect of the drug is shown at the maximum internal use, it is well absorbed, destroying the substances necessary for the generation of the cell membrane of fungi.

Product form

Producing tablets, ketoconazole ointment, candles, shampoo ketoconazole.

Indications

Ketoconazole is prescribed for the treatment of systemic instructions and superficial mycoses: nail fungus, skin fungus, Blastomyces, fungal scalp blastomitsetozov gastrointestinal tract, oral cavity, urinary organs, internal organs.

Ketoconazole is used to prevent infections of fungal nature in patients with reduced immune resistance.

Candles Ketoconazole prescribed for the treatment of chronic, acute vaginal mycosis prevention of fungal vaginal infections.

Instructions for use of ketoconazole

Ketoconazole tablets taken with food. Adults with ringworm take one tablet on the 1st p / day for 2-8ned. For the treatment of chronic candidiasis, onychomycosis take the same dose as much as needed for full recovery (about 4-6ned).

For the treatment of lesions of the gastrointestinal tract, oral cavity, urinary system take one or two tablets / day for 2 weeks, then move on to the use of one tablet / day until recovery (also about 4-6ned).

For the treatment of systemic fungal infections on the instructions of ketoconazole administered two tablets / day for 2 weeks, then - one tablet / day for several months.

As a preventive measure ketoconazole tablets appoint one piece / day.

Children after two years of age are 0, 05gr / day if their weight is not more than 20 kg, and 0 1g, if their weight - 20-40kg.

For the treatment of fungal diseases of the eye is prescribed to take one tablet / day. If found severe lesions of the cornea, apply droplets ketoconazole prepared from a tablet formulation dissolved in 5 ml of boric acid 4 to 5%. Drops was instilled 5-6 times / day in the conjunctival sac.

Ketoconazole ointment is applied to a p / day to the affected area, processing and a healthy portion of about 2cm. Treatment generally lasts for several days.

For the treatment of candidiasis, moldy fungus ketoconazole ointment used 2-3ned .; for the treatment of tinea - 2-6ned .; for the treatment of seborrheic dermatitis - 2-4ned. The ointment is applied to one or two p / day.

 Ketoconazole shampoo

Ketoconazole Shampoo for 3-5min applied on the hair, the scalp, after the wash. For the treatment of seborrheic eczema, dandruff shampoo is used two p / week for 3-4ned. For the treatment of tinea depriving ketoconazole shampoo used every day for 5d.

As a preventive measure to prevent seborrheic eczema, dandruff shampoo is used a p / p per week or one / two weeks.

Vaginal suppositories ketoconazole administered one piece / day for 3-5dn. If necessary, repeat the course before the recovery.

side effects

Usually ketoconazole it is well tolerated, but sometimes when applied externally, it can cause skin irritation, dermatitis contact, itching, increased dryness, oiliness, loss, change in color (gray in patients with chemically damaged hair) hair.

Internal use of ketoconazole can result in vomiting, diarrhea, nausea, cause headache, drowsiness, joint pain, dizziness, gynecomastia, deterioration of libido, alopecia, impaired liver function, skin reactions of intolerance.

Candles ketoconazole may cause burning, itching, and sometimes dizziness, nausea.

Contraindications to the use of ketoconazole

According to the instructions of ketoconazole should not be used during breastfeeding, pregnancy, kidney disorders, hepatic function, hypersensitivity.

You can not simultaneously with ketoconazole tablets to take drugs that lower stomach acid, cimetidine, and like him means anticholinergics.

During therapy should be monitored condition of the blood and liver. Be wary appoint Ketokonizol patients with abnormal function of the pituitary gland, the adrenal cortex.

Children under two years of ketoconazole is prescribed only when there are serious indications.

Shampoo should not be used in the sensitivity to its components. Pregnant and lactating women can use shampoo, because in this form, it does not enter the bloodstream.





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