Kaverdzhekt - synthetic drug used in erectile dysfunction.
Pharmacological action Kaverdzhekta
The active substance Kaverdzhekta promotes relaxation of muscles of the corpora cavernosa, increasing blood flow and improvement of microcirculation, which causes an erection. Kaverdzhekt Review takes effect within 5-10 minutes after the administration, the duration has an effect - from one to three hours.
In addition to the main action, the drug inhibits platelet aggregation.
Kaverdzhekt produced in the freeze-dried dosage form for solution for intracavernosal injection in vials containing 10 or 20 micrograms of alprostadil.
Kaverdzhekta analogs containing the same active substance is not released. The closest mechanism of action medicaments Verona Viagra Viasan-LF, Vizarsin, speaker, Zidena, Yohimbine Spiegel, Levitra, Maksigra, Cialis, Sirbida, Raylis in the dosage form of tablets or capsules.
According to the instructions Kaverdzhekt apply:
- When erectile dysfunction vascular, neurogenic, psychogenic or mixed aetiology;
- For the diagnosis of erectile dysfunction as an adjunct to other diagnostic tests.
The drug is contraindicated according to the instructions Kaverdzhekt apply at:
- Anatomical deformation of the penis, including cavernous fibrosis, angulation of the penis, Peyronie's disease;
- Diseases that lead to the development of priapism, including sickle cell anemia, leukemia, myeloma;
- The presence of penile implant;
- Hypersensitivity to the components installed Kaverdzhekta.
The drug is not applicable in men, which is contraindicated or not recommended sexuality. Application Kaverdzhekta under the age of 18 years has not been studied.
The first few injections Kaverdzhekt should be carried out by specially trained medical personnel. Intracavernous introduction Kaverdzhektom carried out using needles size 13 mm 27-30 G. self-injection can be started only after mastering the art of injection procedure should be carried out in sitting, standing or reclining.
Dose Kaverdzhekta and analogues of the drug is selected individually with the erectile response. When psychogenic erectile dysfunction, vascular and mixed etiology initial dose of 1, 25 mg, a second injection is administered in the amount of 2, 5-7, 5 mg, depending on the answer to the first injection.
When applying Kaverdzhekta recommended to introduce the smallest effective dose is not more than three times a week. Do not enter Kaverdzhekt more than once a day. The recommended average dose is 5-20 mg, the maximum - 60 mg.
As an additional tool for the diagnosis of erectile dysfunction using a single dose of Kaverdzhekta that causes a normal erection. According to the instructions Kaverdzhekt used in pharmacological assays, and as an additional means for visualization and evaluation of penile vascular status during or duplex Doppler ultrasound and arteriography fallografii radioisotope in the sample and elution of xenon-133.
To prepare the solution for intracavernosal administration should use the water for injections with benzyl alcohol 0, 9%, or the supplied solvent. The resulting solution contains 10 or 20 mg of active ingredient. It is not recommended to mix the solution with any other drugs.
In therapy Kaverdzhektom of instructions at the same time should not use other medicines for the treatment of erectile dysfunction.
When the therapy Kaverdzhekt Review often causes:
- Pain and a burning sensation in the penis;
- Penile fibrosis, including angulation of the penis, the formation of fibrotic nodules and Peyronie's disease;
- Ecchymosis at the injection site;
- Prolonged erections;
- Hematoma at the injection site.
Typically, these side effects are associated with the injection technique rather than the action of the active ingredient.
From systemic reactions Kaverdzhekt Review can cause:
- Increased blood pressure;
- Back pain;
- Nasal congestion;
- Flu and pain;
- Upper respiratory tract infection;
Redness and swelling of the scrotum, hematuria, frequent urination, pelvic pain, tachycardia, vasodilation, peripheral vascular disorders, hypoesthesia, rash, muscle weakness, rash, dry mouth, itching, nausea, leg cramps Kaverdzhekt and analogues cause very rarely .
In overdose Kaverdzhektom may develop prolonged erections or priapism, penile pain and irreversible deterioration of erectile function.
Kaverdzhekt refers to a number of prescription drugs. The recommended shelf life of the freeze-dried to prepare a solution - 24 months.