Grandaxinum - a synthetic drug that acts as a tranquilizer daily with a mild stimulating activity.
The main active ingredient Grandaxinum - Tofisopam. It has a tranquilizing activity, reducing anxiety, tension and fear.
It has a sedative effect, but exhibits some stimulatory effect on the central nervous system. It does not cause sleepiness, addiction and withdrawal.
Round, flat, odorless, white tablets. A tablet contains 50 mg of active substance - tofizopama and auxiliaries. The package contains 10 pieces in a carton box - 2 or 6 packs.
Grandaxinum indicated for use in:
- neuroses and neurosis-like conditions caused by emotional stress or autonomic disorders;
- disorder of mental adaptation;
- reactive depression with moderate psychopathological symptoms;
- myopathy, myasthenia gravis, neurogenic muscular atrophy and other pathological conditions with secondary neurotic symptoms;
- premenstrual tension syndrome;
- menopausal syndrome (alone or in combination with hormonal therapy);
- alcohol withdrawal syndrome.
According to the reviews of Grandaxinum, alcohol withdrawal syndrome is best treated in combination with absorbent drugs, reducing such phenomena as nightmares, fears and shaking hands.
Grandaxinum shown at nevropodobnyh states expressed concern, obsessive feelings, apathy, decreased activity, but it can not be applied in the states expressed aggressive, strong and deep agitated depression. Also, disorders of respiratory function such as the syndrome of sleep apnea and respiratory failure (decompensation) is a contraindication to the use of Grandaxinum. The drug should not be used during the first trimester of pregnancy and lactation.
Precautions should be prescribed the drug for angle-closure glaucoma, epilepsy, atherosclerosis decompensated chronic respiratory distress syndrome, acute respiratory failure, and in case of hypersensitivity to the drug.
According to the instructions Grandaxinum should be used with caution with other drugs. Thus, it can not be used simultaneously with sirolimus, tacrolimus, and cyclosporine.
When using with other drugs that suppress the central nervous system (opiates and analgesics) should be borne in mind that according to the instructions Grandaxinum reinforces their action.
Precautions should be combined with antifungal and antihypertensive drugs.
When using Grandaxinum can cause insomnia, confusion, and headache. In some cases, may increase irritability. In patients with epilepsy seizures may occur.
Because allergic reactions are possible itching or rash.
From the digestive system may experience decreased appetite, nausea, constipation, and dry mouth.
In the opinion of Grandaxinum tension or pain in the muscles is rare.
Instructions for use Grandaxinum
In appointing Grandaxinum dosage is calculated individually based on their form of the disease, sensitivity to the drug and the patient's condition.
Standard dosage for adults - 1-2 tablets 1 to 3 times a day, maximum - 6 tablets per day. If necessary, one-time can be taken 1-2 tablets.
When assigning Grandaxinum elderly patients, as well as in renal failure daily dose should be reduced by about 2 times.
When high doses of the drug may occur overdose symptoms: vomiting, respiratory depression, confusion. In these cases, gastric lavage, take the activated carbon and apply appropriate symptomatically. If improvement does not occur - seek medical advice.
Grandaxinum available on medical prescription, drug shelf life - 5 years.