Glucose

 Glucose
 Glucose is an easily digestible source of valuable food, which increases the body's energy reserves and improves its function.

Pharmacological action

Glucose is used as a means for detoxification (removal of toxins from the body) and rehydration (replenishing fluid loss).

Isotonic glucose solution of 5% is applied for fluid replacement. Also, the solution of glucose is a source of nutrient, the metabolism in tissues where a large amount of energy which is necessary for normal functioning of the body.

There are also hypertonic glucose solutions (10-40%), maintained by intravenous increases the osmotic pressure of the blood to improve metabolism and antitoxic function of the liver, enhance fluid flow directed from the tissues into the blood.

Furthermore, the use of hypertonic glucose solution promotes vasodilation, enhancement of the contractile activity of the heart muscle and an increase in urine volume.

As a fortifying agent glucose is used in chronic diseases that are accompanied by physical exhaustion.

Detoxication properties of glucose due to its ability to activate the function of the liver to neutralize toxins, as well as a decrease in the concentration of toxins in the blood by increasing the volume of circulating fluid and amplified urination.

Indications for use of glucose solution

Appointed glucose solution at:

  • hypoglycemia (low blood glucose);
  • failure carbohydrate diet;
  • intoxications, accompanying liver disease (liver failure, hepatitis);
  • poisoning (poisoning provoked by microbes trapped in the diet);
  • hemorrhagic diathesis (disease of the blood system, which manifests itself in the form of increased bleeding);
  • dehydration caused by diarrhea, vomiting, or in the postoperative period;
  • intoxication;
  • collapse (sudden drop in blood pressure);
  • shock.

Glucose can be used for preparing solutions of drugs for intravenous administration, as well as a component antishock and blood fluids.

mode of application

 Glucose
 Glucose 5% may be introduced into an organism by any means (intravenously, subcutaneously, into the rectum), since it corresponds to osmotic pressure osmotic pressure of blood. Hypertonic solutions of glucose are administered only intravenously as their osmotic pressure is much higher than in the tissues and blood.

Raise the level of glucose by oral administration (tablets) are recommended using 0, 5-1 g of the drug per reception. Application of a 5% glucose solution with drip enema involves administering 200 ml, 500 ml or 1000 ml of the drug at once, while the daily dose should not exceed 2000 ml.

5% glucose solution can be administered intravenously (infusion) or subcutaneously in a volume of 300-500 ml.

Hypertonic glucose solution can be assigned a single administration of 10-100 ml or drip 200-300 ml (daily dose).

side effects

Applying the recommended doses glucose usually does not cause undesirable effects. In rare cases, the remedy can provoke fever, hyperglycemia (high blood glucose), acute left ventricular failure, hypervolaemia (increased blood volume), increased production of urine. Local reactions to the use of glucose may appear as thrombosis, bruising, infection development, local pain.

When using 5% glucose as the solvent other drugs the side effects caused action of these drugs.

Contraindications specified in the instruction to the glucose solution

Medication improving glucose levels can be dangerous if:

  • decompensated diabetes (always high blood sugar);
  • impaired glucose tolerance;
  • hyperglycemia;
  • hyperosmolar coma (a special type of diabetic coma);
  • giperlaktatsidemii (elevated levels of lactic acid in the blood of diabetes).

Caution is needed when administered glucose solution for patients with chronic renal failure, hyponatremia, and decompensated chronic heart failure.

Apply glucose during pregnancy and lactation is permitted. It should be remembered that women bear children, the level of glucose in the urine rises, due to hyperglycemia and relatively insufficient production of insulin. In order to prevent the development of diabetes, it is necessary to closely monitor the fluctuations of glucose in pregnancy.

Additional Information

Keep glucose should be an air temperature of 15 0 C to 25 0 C. Shelf life is dependent on the form of the issue - from 2 to 10 years.





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