Gentamicin

 Gentamicin solution
 Gentamicin - an antibiotic with anti-inflammatory action.

Pharmacological action

Gentamicin sulphate belongs to the group of aminoglycosides, it has a broad spectrum of action, being an antibiotic bactericidal action.

Increased activity of the drug exhibits against gram-negative aerobic bacteria: Shigella, E. coli, Salmonella, Enterobacteriaceae, Klebsiella, Proteus, Pseudomonas sticks. Gentamicin acts against staphylococci (even those that are resistant to other antibiotics, penicillin), some strains of streptococci.

Drug resistance meningococcus, pale treponema, some species of streptococci, anaerobic bacteria.

Product form

Producing Gentamicin powder for dilution for injection directly the solution Gentamicin injections, aerosol, gentamicin ointment for external use, and ointment eye cream and drops.

Indications Gentamicin

Gentamicin according to the instructions prescribed for these infections:

  • urinary tract: cystitis, urethritis, pyelonephritis;
  • respiratory tract: empyema, lung abscess, pleurisy, pneumonia;
  • surgical infections: sepsis, peritonitis;
  • Skin: dermatitis, multiple purulent inflammation, trophic ulcers, burns.

Instructions for use Gentamicin

Application Gentamicin is best done after determining the sensitivity to the hair that caused the disease.

The manual shows the average dosages used to treat:

  • urinary tract infections for older teens 14L. and adults the single dose is equal to 0, 4 mg per kilogram body weight, and daily - 0, 8-1, 2 mg per kg of patient weight.
  • In sepsis and other serious infections single dose - 0. 8-1mg per kg, and the daily - 2, 4-3, 2 mg.

The maximum dose of - 5 mg per kilogram per day.

Children under 14 years of Gentamicin Sulfate prescribed only for special reasons.

The daily dose for infants and newborns - 2-5mg per kilogram. Children from 1-5l. appointed 1, 5-3, 0mg per kilogram, children 6-14l. - 3 mg per kilogram.

The maximum dosage of Gentamicin for children of different age groups - 5 mg / kg / day.

The daily dose is normally divided into two or three doses. The course lasts on average 7-10dn. Gentamicin injections usually do 2-3dn intravenously, and then move on intramuscular injection.

 Gentamicin ointment
 For administration by intramuscular use Gentamicin sulfate in the form of ready-made solution or dilute 2ml. sterile water powder. For intravenous injections Gentamicin can only use a ready solution.

Cream or ointment Gentamicin is used in purulent skin inflammation, folliculitis, abrasions. Thus, the affected area two to three lubricated r / day for one to two weeks.

When conjunctivitis, keratitis and other infectious eye diseases apply drops Gentamicin - three or four p / day.

side effects

Application Gentamicin can cause such side effects: nausea, vomiting, hyperbilirubinemia, increased activity of hepatic transaminases, proteinuria, microscopic hematuria, oliguria, renal insufficiency, headaches, hearing loss, drowsiness, irreversible deafness, vestibular disorders, impaired nerve conduction and muscle, skin rashes, fever, itching, angioedema (rare).

Contraindications

The instructions Gentamicin stated that its use is contraindicated if the patient is found hypersensitivity to all antibiotics aminoglycoside.

Also, do not use Gentamicin with neuritis of the auditory nerve, severe functional disorders of the kidneys, pregnancy, lactation, uremia.





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