Gangleron - synthetic drug used in the treatment of functional bowel disorders.
Pharmacological action gangleron
The drug is able to inhibit the transmission gangleron nervous excitement to preganglionarnah postganglionic fibers, due to their ability to block N-cholinergic receptors of autonomic ganglia and causes relaxation of smooth muscles, has a depressing effect on the adrenal chromaffin tissue and carotid glomeruli, expands blood vessels, has anti-ulcer, ganglion-blocking, mestnoanesteziruyuschee , antispasmodic and vasodilatig action.
According to the instructions gangleron released in 2 ml of 1% 5 vials of 10 pieces. in units and 0, 04 g capsules 50 pcs. in packages. One capsule contains 40 mg gangleron the same name of the active ingredient and milk sugar. One ml of a solution containing 30 mg gangleron homonymous active agent and water for injection.
Analogues gangleron of the active substance is not released. By analogues gangleron mechanism of action and of belonging to a group of pharmacological drugs include:
According to the instructions gangleron prescribed in the treatment of biliary dyskinesia, acute cholecystitis, acute hepatitis, simpatoganglionita, chronic hepatitis, gangliosolyarita, chronic cholecystitis, cholangitis and postcholecystectomy syndrome, and for the prevention of angina attacks.
In accordance with the instruction gangleron applied intramuscularly 1 ml of three or four times on the first day of treatment, after which the dose is increased to 2-3 ml three times or four times a day. After 10 days of treatment, injection was replaced with capsules which take up meal inside with water. In the treatment of fibrocystic breast prescribe taking one capsule during meals for 2-3 weeks.
In accordance with the instructions gangleron contraindicated in hypersensitive to the components of the drug, as well as hypotension, liver failure, chronic renal failure, and degenerative changes in the central nervous system.
Side effects gangleron
Application Review gangleron causes allergic reactions, tachycardia, fatigue, dry mouth and dizziness. Also gangleron Review falling on language causes irritation, and intravenous administration - memory loss, constipation, intestinal, orthostatic collapse, and urinary retention.
In accordance with the instructions gangleron must be stored out of reach of children and protected from light, dry place at room temperature to 25 ° C. Shelf life of the drug, subject to the recommendations of 2 years.