Ftivazid - drug
remedy for tuberculosis.
Structure and Composition ftivazid
The drug is produced in the form of tablets. Each tablet contains the active ingredient - ftivazid 100 mg.
The blister packs of 10 tablets or in dark glass jars of 100 tablets.
Pharmacological action ftivazid
According to the instructions ftivazid a TB drug, a derivative of isonicotinic acid hydrazide.
Active against Mycobacterium tuberculosis. Use of the drug inhibits metabolic and oxidative processes leading to membrane damage mycobacteria inhibits the synthesis of nucleic acids has an effect on Mycobacterium at all levels.
According to the instructions ftivazid designed to treat all forms of TB in children and adults.
Dosing and dosing regimen
The drug is taken orally.
Usually, the dosage for adults is 5 pills two or three times a day. Children take medication based 30-40 mg per kg body weight per day divided into three doses.
When lupus dosage is 3 tablets three to four times a day. Duration of treatment is 1-1, 5 months. If necessary, you can pass a second course of treatment after a two-month break.
The maximum dose of the drug for adults: single - 10 tablets daily - 20 tablets. For children: daily - 15 tablets.
The instructions to ftivazid contain the following contraindications:
- Hypersensitivity to the drug;
- Chronic heart failure of 2-3 degrees;
- kidney or liver disease;
- organic lesions of the CNS;
- chronic renal failure;
In the opinion of ftivazid
may cause the following side effects:
- The sense organs and nervous system: dizziness, euphoria, headache, fatigue, memory loss, sleep disturbances, depression, psychotic reactions, optic neuritis, peripheral neuritis.
- Gastrointestinal tract: loss of appetite, vomiting, dry mouth, nausea, hepatitis, epigastric pain.
- The cardiovascular system and the hematopoietic system: increased bleeding, kardialgiya.
- Allergic reactions: skin rash, fever.
- Endocrine system: menorrhagia, gynecomastia.
In the opinion of ftivazid in patients with epilepsy can cause increased frequency of epileptic seizures.
Application ftivazid during pregnancy and breastfeeding
During pregnancy, the drug should be taken with caution, given the benefits to the mother and the potential risk to the fetus.
At the reception ftivazid recommended to interrupt breastfeeding.
Drug interaction ftivazid
Ftivazid increases the side effects of alcohol, acetaminophen, carbamazepine, benzodiazepines gepatoksicheskih preparations. Also enhances the effect of anticoagulants and antiplatelet agents, and decreases - glucocorticoids and mineralocorticoid.
Slow down absorption of the drug antacids.
At the time of dosing it is recommended to conduct regular eye examination.
At the same time it is expedient to appoint ftivazid vitamins B6 and B1 for the prevention of neuritis.
During the drug should avoid driving and other mechanisms that require high concentration of attention.