Fozikard - a means to lower blood pressure.
According to the instructions Fozikard
It refers to the group of ACE inhibitors. The product contains the active ingredient - fosinopril. In the body it is converted to its active metabolite, the ability to inhibit angiotensin converting enzyme (ACE) inhibitors. As a result, the body breaks down the chain of biochemical reactions, angiotensin-I is not converted to angiotensin-II, it is realized ine vasoconstrictor and thus increases the pressure effect. This drug does not alter the blood circulation in the kidneys, the brain or muscles.
Eliminating vasospasm, Fozikard reduces the total peripheral vascular resistance, and hence blood pressure. The drug reduces the pre- and afterload on the heart muscle. As a result, the treatment is slowing the destruction of bradykinin - a biologically active substance that dilates blood vessels.
Once inside Fozikard well absorbed, eating can slow the rate of absorption. The therapeutic effect begins to appear within 1 hour, he is maximal in 2-6 hours after ingestion and lasts throughout the day. Therefore, to achieve lower blood pressure enough to take Fozikard 1 per day.
The conversion of the drug occurs in the digestive tract and the liver, excretion via the kidneys and in bile.
Fozikarda analogues are such drugs on the basis of fosinopril as Monopril, Fozinotek.
Fozikard by manual release tablets of 5, 10 or 20 mg.
The drug is used for high blood pressure in the treatment of chronic heart failure.
Do not take the drug in case of intolerance of its constituent components, in the case of idiopathic or hereditary angioedema in the past, including when it arose in response to the reception of other analogues Fozikarda from the group of ACE inhibitors.
With care, you can use the medication in the case of renal and chronic heart failure III and IV, diabetes, systemic connective tissue diseases, some heart diseases and kidney diseases, the elderly, if you want to keep to a diet with restriction of salt.
There are no reviews of Fozikarde in terms of the safety of its children under 18 years old and pregnant and lactating women.
Instructions for use Fozikarda
The tablets are taken orally as a whole, regardless of the meal, washed down with water. The therapeutic dose and rate of admission are selected in each case individually. A few days before the course is recommended to cancel other antihypertensive agents. When there is no option to cancel diuretics Fozikarda dose must not exceed 10 mg / day.
When hypertension Fozikard begin taking 10 mg 1 time a day, watching the change in pressure. If the desired pressure level is reached, the dose can be gradually increased up to 40 mg / day (this is the maximum dose). If insufficient monotherapy lowers blood pressure, the treatment can be enhanced by addition of diuretics.
combined treatment of chronic heart failure begin receiving Fozikarda 5-10 mg 1 time a day, if necessary, increase the dose gradually. The doctor should monitor every dosage increase.
In diseases of the liver and kidney dose reduction is required.
In an application with antacids reduces absorption Fozikarda and, therefore, its therapeutic effect is not fully. So between taking these medications should be kept interval for 2 hours.
Side effects Fozikarda
In the opinion of Fozikard can cause nausea, disorders stool, abdominal pain, vomiting, reduction of hemoglobin and white blood cell count, headache, emotional lability, insomnia, blurred vision, decreased urine production, allergic reactions.