Fluoxetine - is a drug
a drug belonging to the group of antidepressants.
The pharmacological action of Fluoxetine
Fluoxetine relates to propylamine. Its mechanism of action is due to selective (selective) the ability to inhibit the reuptake of serotonin in the central nervous system. This drug has minimal effect on the exchange of dopamine, acetylcholine and norepinephrine.
The instructions to fluoxetine noted that the drug reduces the feeling of tension and fear, relieves anxiety, improves mood. Fluoxetine does not cause orthostatic hypotension, has no negative effect on the myocardium.
Feedback from fluoxetine to achieve full therapeutic effect should be at least one to two weeks.
Fluoxetine is well absorbed from the gastrointestinal tract. Food intake has no significant effect on bioavailability.
The drug is taken in the following cases:
- Treatment of depressive states of varying severity;
- Obsessive-compulsive disorder;
- Eating disorders (anorexia, bulimia);
- Combined therapy of alcoholism.
For the treatment of depression is usually prescribed drug intake 1 tablet (20 mg) once a day, preferably in the morning. In case of insufficient effectiveness of the dose may be increased to two tablets (40 mg) per day. The maximum allowable daily dose is 4 tablets (80 mg), and for elderly patients - 3 tablets (60 mg).
According to the instructions of fluoxetine for the treatment of bulimia assigned one tablet three times a day.
For the treatment of obsessive-compulsive disorder administered 1 to 3 tablets (20-60 mg) per day.
The duration of treatment depends on the severity of the disease, the effectiveness of the therapy. The minimum duration of the course - at least 3 weeks, and the maximum - a few years.
Fluoxetine: side effects
Therapy of this drug may lead to side effects:
- From the nervous system -Head pain, fatigue, dizziness, weakness, anxiety, mania, anxiety, increased risk of suicide;
- On the part of the digestive system - decreased appetite, indigestion, dry mouth, excessive salivation, or vice versa (salivation);
- From the other organs - decreased libido, increased sweating, weight loss, allergic reactions.
If you use Fluoxetine side effects of the therapy often require its abolition.
According to the instructions of fluoxetine is contraindicated in the following cases:
- Individual intolerance to the drug;
- Atony of the bladder;
- Angle-closure glaucoma;
- Severe liver or kidney failure;
- Treatment of MAO inhibitors;
- Pregnancy and lactation;
- Increased risk of suicide;
- Prostatic hypertrophy.
Fluoxetine in patients suffering from Parkinson's syndrome, epilepsy, diabetes, or a sharp depletion requires special care.
Fluoxetine interaction with other drugs
means enhances the effects of alcohol, drugs and Diazempama lowering blood glucose levels.
Fluoxetine while receiving tricyclic antidepressants increases their concentration in the blood plasma almost doubled.
In the opinion of fluoxetine should not be prescribed to patients on the background of electroconvulsive therapy, as in this case it is possible weighting seizures.
In case of accidental or deliberate taking a large dose of Fluoxetine patient needs acute care. No specific antidote, therefore symptomatic treatment. To speed up the elimination of the drug from the body is carried out gastric lavage and sorbents are inside.
Fluoxetine is available in capsules containing 20 mg of active substance.
The drug is released from pharmacies only by prescription. Store at room temperature out of reach of children. Shelf life - three years. Fluoxetine should not be used after the expiration date printed on the box.