Farmazolin - alpha-agonists.
Structure and Composition
The drug release
two dosage forms:
- Nasal drops of 0, 05% or 0 to 1% in bottles of 5 or 10 ml.
- Nasal Spray 0, 1%, in bottles of 15 or 20 ml.
The active ingredient of the drug - xylometazoline.
Pharmacological action Farmazolina
The drug produces a vasoconstrictor and antikongestivny effect. Constricts blood vessels of the nasal mucosa, stimulates alpha-adrenergic receptors, reduces congestion, exudation and blood flow in the venous sinuses. In the opinion of Farmazolin facilitates nasal breathing.
The drug produces a local effect, which occurs five minutes after the administration and lasts for one to two hours.
According to the instructions Farmazolin shown at:
- acute rhinitis of various origins;
- Otitis media (to reduce swelling of the mucous membrane of the nasopharynx);
- diseases of the paranasal sinuses (in order to facilitate the outflow of secretion);
- surgical and diagnostic procedures in the nasal passages (to reduce bleeding and edema).
According to the instructions Farmazolin is contraindicated in:
- angle-closure glaucoma;
- children aged up to six months;
- atrophic rhinitis;
- hypersensitivity to the drug;
Dosing and dosing regimen Farmazolina
Farmazolin 0, 05%, as a rule,
administered to children under the age of twelve years, and in patients who have not previously used vasoconstrictor drugs.
Children from six months to five years is prescribed drug in a dosage of 1-2 drops of up to two times per day.
Children from five to twelve years, the dosage is 1-3 drops of up to two times per day.
Adults and children over twelve years, appoint Farmazolin 0, 1% 1-3 drops intranasally up to three times a day.
The duration of treatment ranged from three to five days. Do not use the drug longer than seven days.
Application Farmazolina during pregnancy and breastfeeding
At therapeutic doses the drug has no systemic impact, acting locally, so it is not contraindicated.
Side effects Farmazolina
In the opinion of Farmazolin can cause side effects, manifested as a dry nose, burning and tingling. Too frequent or prolonged use at high doses Farmazolin Review leads to swelling of the nasal mucosa. You may experience increased blood pressure, dizziness, insomnia, headache, palpitations, transient blurred vision, irregular heartbeat.
Especially in long-term use of the drug dosage is too high can lead to a depressive state.
Enhances the effects of other agonists Farmazolina groups.
Simpatolitiki and adrenolytics and calcium antagonists weaken the effect of the drug.
Farmazolin enhances the hypertensive effect of MAO inhibitors and tricyclic antidepressants serdechnoso-sudistuyu system.