Famvir - an antiviral agent.
Pharmacological action Famvir
Famvir is an antiviral agent penciclovir form for oral administration. It is active against herpes viruses type 1 and 2, cytomegalovirus, Epstein-Barr virus and varicella-zoster virus. Once in the virus-infected cells, it is converted to triphosphate and inhibits the replication (reproduction) of the viral DNA. Famvir is not able to influence the healthy, virus-free cells. Viruses produced virtually no resistance to the drug, including in patients with reduced immunity.
In the opinion of Famvir reduces the pain of neuralgia caused by herpes zoster.
In the studies the drug was safe with respect both gene mutations in bacteria and in mammals.
The drug is almost completely and rapidly absorbed from the digestive tract, its bioavailability is 77%. The body converts it into an analogue penciclovir Famvir. Withdrawal from the body in metabolizing a partially carried out through the kidneys.
Analogues of Famvir is Famciclovir and Minaker.
By Famvir instructions provided in the form of tablets for 0, 125, 0, 25 and 0, 5 g
Indications for use Famvir
The drug is indicated for the treatment of infectious diseases caused by herpes virus type 1 and 2. It is effective in the primary infection when symptoms first appeared, and exacerbation of chronic infection labial and genital herpes. Famvir is also valid for the cytomegalovirus and the herpes zoster virus, including postherpetic neuralgia with eye complications (ophthalmoherpes).
The drug is not used in case of intolerance to it and pentsiklavira. Reviews of Famvir in children under 18 years is not, therefore, in the appointment of the drug, they should weigh the risk / benefit ratio.
Instructions for use Famvir
The tablets are taken orally without chewing, independent of meals. The most effective Famvir show when to begin treatment as early as possible after symptoms appear (at the stage of itching and tingling, and herpes zoster).
In the case of herpes zoster in humans with a normal immune status, as well as their dosage oftalmogerpese be 0, 5 g of 3 times a day for the duration of the course of 7 days. This reception mode reduces the neurological manifestations of the disease.
In the acute phase of herpes zoster for getting rid of skin rashes recommended intake 0, 25 g 3 times a day, or 0, 5 g, 2 times a day. Chance of a single dose of the daily dose 0 75 The course lasts for 7 days.
When herpes zoster in people with depressed immune recommended intake of 0, 5 g 3 times a day in the course of 10 days.
For treatment of primary genital herpes with normal immunity dose of 0, 25 g of 3 times a day for 5 consecutive days, in case of relapse - 1 g 2 times a day for 1 or 0 125 g, 2 times a day for 5 days.
Recurrence of herpes labialis with normal immune status are treated once-daily 1, 5 g, or at 0, 75 g, 2 times a day for 1 day.
When labial and genital herpes due to lower immunity recommended intake of 0, 5 g 3 times a day for 7 days.
Genital herpes is transmitted from person to person through sexual contact, and during exacerbations of the risk of infection is particularly high.
If the kidney function dose of Famvir reduces manual.
For elderly patients with well-preserved kidney function to adjust the dose is not necessary.
In the opinion of Famvir can cause occasional nausea, mild headaches, vomiting, dizziness, skin rashes. When lowered immunity sometimes abdominal pain.