Ethambutol is an anti-TB drug, which is effective for the treatment of tuberculosis at different stages of the tide. The drug has a bacteriostatic, anti-microbial, anti-inflammatory and healing action.
Ethambutol prescribed as monotherapy, and in the complex treatment of diseases of the respiratory system.
Structure and Composition
The main active ingredient - Ethambutol 0, 4 g
Auxiliary components: ethylene, talc, propylene glycol, a food dye.
Ethambutol comes in tablets to 0, 4 g placed in a carton 50-100 pieces.
Pharmacological properties Ethambutol
Ethambutol actively penetrate into the cells of mycobacteria prevents their reproduction and development, and also violates the cellular metabolism and destroying infections in the respiratory tract. The drug is effective for the elimination of Streptococcus, Staphylococcus, and Mycobacterium tuberculosis. Ethambutol eliminates even bacteria that are resistant to other anti-TB drugs.
Upon receipt of the therapeutic effect of the drug is achieved within one day. Ethambutol absorbed 80% and reaches a maximum plasma concentration within 24 hours. The concentration in the lungs is greater than the concentration in the blood, 6-8 times. The drug creates several inactive metabolites actions that are excreted by the kidneys in urine and faeces.
Ethambutol prescribed for the treatment of tuberculosis at different stages of the course and serious diseases of the respiratory system.
In accordance with instructions prescribed Ethambutol taken after meals one time per day to 15 mg. Dosage can be increased to 25-50 mg two times a day (depending upon the stage of tuberculosis). The course of treatment lasts 2-3 months.
After the main course of treatment for 2-3 weeks a maintenance dose - 10 mg 1 time a day.
The maximum daily dose for adults Ethambutol should not be more than 2 years The drug should not be prescribed to children under 13 years of age and with 13 years the dosage is 15 mg 1-2 times a day. The daily dose for children should not exceed 1 year
The general course of treatment for tuberculosis in the severe stage of the flow lasts from 9 months to 2 years.
According to the instructions Ethambutol should not be administered to patients with impaired liver function and kidney function and severe disease of the heart and the digestive tract is assigned to the minimum dose of the drug.
During treatment, periodic ophthalmologic examination, monitor the functioning of the cardiovascular and nervous systems.
Contraindication to Ethambutol are hypersensitivity and intolerance to the components of the drug, blurred vision and cataracts, inflammatory eye disease, diabetes, kidney and liver failure, pregnancy and lactation, children under 13 years.
Precautions The drug should be taken in patients driving or working in hazardous objects. Ethambutol may reduce the concentration of attention and cause confusion.
Side effects Ethambutol
Local side effects Ethambutol: skin rash, itching, burning, redness of the skin, hives, dermatitis.
Systemic side effects: depression, anorexia, headache and dizziness, disorientation, hallucinations, optic atrophy, decreased visual acuity, dyspeptic disorders, liver function and kidney failure, leukopenia, arthralgia.