The preparation contains the active substance metiletilpiridinola hydrochloride as excipients using water for injection, a solution of sodium hydroxide.
Pharmacological properties emoksipin
The drug belongs to the group of antioxidants is angioprotectors. Like its counterparts Emoksipin reduces vascular permeability, inhibits free radical processes. When using emoksipin decreases blood viscosity and platelet aggregation, increases the content of nucleotides (cyclic guanosine monophosphate and cyclic adenosine monophosphate) in the tissues of the brain and platelets. The drug has fibrinolytic activity, reduces the risk of hemorrhage. Has expanding effect on the coronary vessels, myocardial infarction prevents the spread of necrosis. It improves the function of the cardiac conduction system and contractility.
Emoksipin has a hypotensive effect. The data obtained from the medical review Emoksipin in violation of cerebral circulation ischemic origin improves neurological symptoms.
Drug metabolism occurs in the liver. The half-life of the drug - 18 minutes. Write mainly kidneys.
In neurosurgery and neurology Emoksipin used in the treatment of:
- the recovery period after a hemorrhagic stroke;
- coming cerebrovascular;
- ischemic stroke;
- operating after intracerebral hematomas;
- in the treatment of traumatic brain injury.
In cardiology, the drug is used in combination therapy with:
- prevention of reperfusion syndrome;
- acute myocardial infarction;
- unstable angina.
- Children up to 18 years;
- pregnant women;
- idiosyncrasy of the active drug substance.
Emoksipin Dosage and instructions for use
Neurosurgery and Neurology: intravenously 10 mg / kg / day by infusion of 20-30 drops / minute for 10-12 days. In the following days the drug is administered intramuscularly at 60-300 mg 2-3 times a day for 20 days. The preparation is diluted before administration in a solution of sodium chloride (200 mL).
Cardiology: Emoksipin drug solution is injected intravenously 1-3 times a day by infusion of 20-40 drops / minute dose of 600-900 mg. The course of treatment is 5-15 days. With subsequent replacement by intramuscular injection 2-3 times per day. Dosage intramuscular injection of 60-300 mg, 10-30 days.
Side effects emoksipin
- clotting disorder;
- allergic reactions;
- chest pain;
- high blood pressure;
- injection site reactions (pruritus, pain, burning sensation);
Interaction with other drugs
Like some of his peers, he has Emoksipin pharmaceutical incompatibility with other medicines.
Overdose emoksipin reviews or research results there.
During the treatment emoksipin should monitor blood clotting and blood pressure.
Shelf life emoksipin
two years. After the expiry date the drug should be disposed of.
Emoksipin stored in a dark place at room temperature.