Ekodaks - an antifungal drug.
Structure and Composition Ekodaksa
The drug is released as a 1% cream for topical application comprising an active ingredient - econazole nitrate 10 mg / g.
Additional components: concentrated phosphoric acid, mineral oil, sodium dihydrogen phosphate dihydrate, sodium hydroxide, white soft paraffin, cetostearyl alcohol, chlorocresol, purified water, cetomacrogol 1000.
The aluminum tubes of 10 g
Imidazole derivative is econazole and has on the antifungal, bactericidal and fungicidal action. Ekodaksa mechanism of action due to the suppression of the biosynthesis of ergosterol, regulating the permeability of cell walls of microorganisms.
Application Ekodaksa active against fungi, yeast and dermatophyte (Microsporum audouini, Torulopsis, Rhodotorula, Trichophiton rubrum, Microsporum gypseum, Trichophiton mentagrophytes, Malassezia furfur, Microsporum canis, Trichophiton tonsurans, Candida albicans), causing pityriasis versicolor, as well as against some Gram-positive bacteria (Staphylococcus, Streptococcus and Nocardia minutissima).
According to the instructions Ekodaks prescribed in the following cases:
- dermatomycosis skin, in particular feet, including complicated superinfection (gram-positive bacteria);
- candidiasis of skin;
- fungal infections of the ear canal;
- pityriasis versicolor.
Dosing and dosing regimen Ekodaksa
According to the instructions Ekodaks designed exclusively for outdoor use.
Children older than 16 years and adult drug applied to the affected skin smooth thin layer until completely absorbed. The drug is applied once a day - in the morning or in the evening.
Moist areas in the folds of the skin must first be dried with gauze.
In the treatment of onychomycosis cream is applied once a day under an occlusive dressing.
The duration of therapy is not more than two weeks. The only exception is the treatment vysokokeratinizirovannyh sites. In this case, the treatment allowed Ekodaksom reviews for over one and a half months.
According to the instructions Ekodaks contraindicated:
- under the age of 16 years;
- if you are hypersensitive to one or more components of the drug.
Side effects Ekodaksa
In the opinion of Ekodaks well tolerated by patients. Sometimes you may experience local reactions (burning and itching, contact dermatitis, redness and irritation of the skin, blisters, exfoliative skin lesions, rash, skin atrophy, hypopigmentation). Hypersensitivity reactions and angioedema Ekodaks Review is in a few cases.
When side effects of drug treatment should be discontinued.
When using the cream should not be allowed contact with eyes.
If therapy Ekodaksom no results for two weeks, you should consider alternative methods.
Application Ekodaksa during pregnancy and breastfeeding
During pregnancy, the drug is not recommended, as there is its systemic absorption.
There is no evidence that econazole passes into breast milk, so Ekodaksa allowed to use during breastfeeding, but only on strict conditions. Do not apply the drug on the chest and nipples.
In the systemic action econazole inhibits CYP 3A / 2C29. However, since the drug Ekodaks poorly absorbed into the systemic circulation, the occurrence of significant interaction unlikely.
Caution should be used in combination with Ekodaks oral anticoagulants (warfarin, acenocoumarol) and to watch closely for blood clotting.