Lekrolin - a drug used in ophthalmic practice and possessing anti-allergic effect.
The pharmacologically active substance in the preparation is in the form of cromoglicic acid sodium cromoglycate (its therapeutic role will be discussed below). Lekrolin available in a single dosage form - drops - but it has two different forms of production:
- lekrolin drop in flakonah- 10 ml. The bottle is made of white polyethylene and the plastic stopper is provided with a dropper;
- lekrolin drop in disposable tube-looks, soldered together. The package may be either 20 or 30 of these tubes. The capacity of each of them - 0, 25 ml.
The concentration of droplets in the vial Lekrolin like and in the same tubes, droppers: 2% (20 mg of sodium cromoglycate in 1 ml solution).
The manufacturer of this drug is a Finnish pharmaceutical factory "Santen".
It is always useful to know how the drug can be replaced with a particular drug, in his absence in the pharmacy. Drops lekrolin - no exception, so here they will be listed synonyms of the drug.
Thus, analogs Lekrolin identical, including the dosage form and may be considered:
- High-chrome (UK);
- Chrome-allergic (Romania);
- Allergen-Chest (Germany);
- Kromogeksal (Germany);
- Kromoglin (Germany);
- Ifiral (India).
It should be noted that all of these drugs are registered by Ministry of Health and to date in the Russian pharmacies.
The main "actor" drops lekrolin - cromoglicic acid - is a so-called mast cell stabilizers. Did not everyone knows that are mast cells. These are specialized cells involved in the immune response to the invasion of a foreign agent, and directly involved in allergic and inflammatory processes. So: by stabilizing cell membranes cromoglicic acid prevents the exit from it of inflammatory mediators (histamine, leukotrienes, and other lymphokines.), Thereby arresting the inflammation and other allergic reactions.
This win allowed the pharmacological action of positive feedback about lekrolin patients, as these drops reduce the need for glucocorticosteroids frequently used in conjunctivitis. Well, judging by the reviews of lekrolin, the drug has established itself in the prevention of allergic reactions in ophthalmic practice.
It should be noted that the drops Lekrolin ineffective conjunctivitis caused by bacteria or viruses.
Here is the testimony that indicated in the instructions to lekrolin:
- allergic conjunctivitis, i.e. inflammation of the mucous membrane of the eyeball of an allergic nature (not infectious);
- keratitis, allergic (allergic inflammation of the cornea);
- keratoconjunctivitis (symptom that combines the two above-mentioned pathological reactions);
- irritation of the eyes, caused by physical and chemical factors (household chemicals, medicines, industrial hazards, pollen, cosmetics, animals horny scales).
According to the reviews of lekrolin full anti-allergic effect of the drug can be expected to range from a few days to a week or two.
Regulations on the use of lekrolin
The standard dosage of the drug prescribed by doctors (it is in the instructions to the lekrolin) - 1-2 drops into the affected eye four times a day.
If you are using a tube-dropper, the contents of one of the tube will last for one landfill in both eyes.
Tube one-time, so even if after putting it remained a drug, it should be discarded.
Contraindications to dropwise lekrolin is their idiosyncrasy. Moreover, it is more often present than the active substance, and one of the subsidiary: benzalkonium chloride (it contains only Lekrolin discharged in vials).
In the opinion of lekrolin contact lens users in such cases it is better to use the drug in tubes, droppers, as they do not impede the healing of wounds from the contact lenses of the conjunctiva and cornea.
Lekrolin during pregnancy
Local drug use and virtually no absorption (and that was absorbed, eliminated from the body within just a few minutes) make it possible to use drops lekrolin during pregnancy.
The mechanism of action involves the development lekrolin not any side effects. The only thing you can expect - a short-term discomfort and slight local irritation. As mentioned above, contained in vials lekrolin benzalkonium chloride can potentially cause severe corneal epithelial cells. Judging by the reviews of lekrolin, allergic reactions to the drug in the form of tubes, droppers were noted. But Lekrolin Patients, however, can cause similar symptoms in the form of blepharitis, inflammation of the eyelid skin or conjunctivitis.
On the professional activity, including to study, Lekrolin has no absolutely no effect (so careless students or students can not rely on an exemption from training).
All this does not mean that Lekrolin vial is any danger to the eye. This is not true. All the negative side effects when used are rare.
Overdose Lekrolin drops in medical practice are not registered.
Lekrolin released from pharmacies without a prescription.
Instructions for storage lekrolin
The drug should be stored at room temperature. Important clarification: Lekrolin, as well as many other drugs used in ophthalmology, should be kept in place, preventing from it out of direct sunlight.
Shelf-life of the drug, which is determined by the manufacturer, is 3 years. But this is true only for unopened packages of medicament. If the vial is opened, then it should be completely consumed within 1 month. As for the tubes, then, as mentioned above, they are thrown out with the residue of the drug (if any) immediately after use.
Opening the package with a tube-droppers Lekrolin (and there are, as we may be from 20 to 30) and must be fully used within 1 month.